Results 71 to 80 of about 24,859 (201)
Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress
Plant, Cell &Environment, EarlyView.ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee +5 more
wiley +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Argonauts Of The Western Pacific
Setelah pembahasan yang agak panjang tentang ilmu sihir, sekarang kita dapat kembali lagi ke deskripsi tentang Kula. Sejauh ini, kita hanya membahas satu kejadian di dalamnya, ekspedisi luar negeri antara Sinaketa dan Dobu, dan kunjungan balasan. Namun, dalam membahas satu tahap khas ini, kita telah memperoleh gambaran tentang seluruh Kula, dan secara ...
openaire +2 more sources
Acta Physiologica, Volume 242, Issue 9, September 2026.ABSTRACT MicroRNAs (miRNAs) have emerged as central regulators of pancreatic islet biology, influencing β‐cell development, proliferation, and function. In type 2 diabetes (T2D), both adaptive and maladaptive miRNA responses shape β‐cell compensation and progressive secretory dysfunction.
Lena Eliasson +3 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Novel (S)‐5′‐guanidinopropyl uridine analogs bearing 2′‐O‐methyl or 2′‐fluoro substitutions enhance nuclease resistance and mismatch discrimination while preserving A‐form RNA structure and potent RNAi activity. These modifications provide a promising strategy for improving the stability, specificity, and therapeutic potential of siRNA‐based medicines.
Sugahara Masaki +3 more
wiley +1 more source
Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
Nature Communications, 2017 While RNA interference is a highly conserved mechanism of gene regulation, how Argonaute-bound small RNAs are targeted for degradation is not well understood.
Paola Pisacane, Mario Halic
doaj +1 more source
Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles
BioEssays, Volume 48, Issue 8, August 2026.Mitotic cells produce three EV types: exosomes and microvesicles (green/blue) delivering pre‐formed molecules, and midbody remnants (magenta) containing functional ribosomes and translation machinery within biomolecular condensates. Unlike passive cargo carriers, MBRs actively synthesize proteins after release, transforming from cellular debris to ...
Ahna R. Skop
wiley +1 more source
MicroRNAs in Spinal Cord Injury: Molecular and Translational Insights
Brain and Behavior, Volume 16, Issue 8, August 2026.MicroRNAs (miRNAs) modulate secondary injury cascades following spinal cord injury (SCI), including inflammation, oxidative stress, apoptosis, and demyelination. Key miRNAs such as miR‐21, miR‐124, miR‐219, and miR‐223 exert neuroprotective effects by regulating astrocytic response, axon regeneration, and remyelination.
Seyyedeh Fahimeh Talebi +3 more
wiley +1 more source
Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute
Nature Communications, 2016 Argonaute proteins are important in the silencing machinery with some regulatory RNAs. Here, the authors solve the structure of an argonaute protein in complex with both the guide RNA and target DNA and propose a mechanism for their recognition.
Tomohiro Miyoshi +3 more
doaj +1 more source