Results 101 to 110 of about 2,559,828 (152)

Aristolochic Acid I Metabolism in the Isolated Perfused Rat Kidney

, 2016
Aristolochic acids are natural nitro-compounds found globally in the plant genus Aristolochia that have been implicated in the severe illness in humans termed aristolochic acid nephropathy (AAN).
David R. Taft (2125321), Robert A. Rieger (2125327), Tomoko Freshwater (2125330), M. Cecilia Torres (2125324), Charles R. Iden (2082190), Manuel A. Barbieri (103566), Horacio A. Priestap (103562), Kathleen G. Dickman (1961947)   +7 more
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Molecular Imaging Mass Spectrometry [PDF]

Kemija u Industriji, 2009
Molecular imaging mass spectrometry (IMS) is a recently developed method for direct determination of spatial distribution of biopolymers, preferably proteins on cell surface and tissues.
Kovac, S., Josić, D.
doaj  

Effects of tumor necrosis factor-α inhibition on kidney fibrosis and inflammation in a mouse model of aristolochic acid nephropathy. [PDF]

Sci Rep, 2021
Taguchi S, Azushima K, Yamaji T, Urate S, Suzuki T, Abe E, Tanaka S, Tsukamoto S, Kamimura D, Kinguchi S, Yamashita A, Wakui H, Tamura K.   +12 more
europepmc   +1 more source

Urothelial malignant disease and Chinese herbal nephropathy

, 2001
We have previously reported occurrence of a specific type of nephropathy due to ingestion of Chinese herbs (Chinese herbal nephropathy [CHN]) In two patients In the UK.
Cook, T, Schmeiser, Heinz H, Terry Cook, Arlt, Volker M.; id_orcid, Volker M Arit, Arit, Volker M, Charles D Pusey, Lord, G M, Cook, Terry, Heinz H Schmeiser, Williams, Gordon, Graham M Lord, Lord, Graham M, Gordon Williams, Williams, G, Pusey, C D, Pusey, Charles D, Schmeiser, H H   +17 more
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Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin‑mediated autophagy. [PDF]

Mol Med Rep, 2021
Lin F, Liu Y, Tang L, Xu X, Zhang X, Song Y, Chen B, Ren Y, Yang X.   +8 more
europepmc   +1 more source

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy

, 2009
Aristolochic acid (AA), present in Aristolochia species, is the major causative agent in the development of severe renal failure and urothelial cancers in patients with AA nephropathy. It may also be a cause of Balkan endemic nephropathy.
Phillips, David H, Burckhardt, Gerhard, Bahn, Andrew, Arlt, Volker M., Glatt, Hansruedi, Arlt, Volker M; id_orcid, Phillips, David H., Bakhiya, Nadiya   +7 more
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Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis. [PDF]

JCI Insight, 2022
Sasaki K, Terker AS, Tang J, Cao S, Arroyo JP, Niu A, Wang S, Fan X, Zhang Y, Bennett SR, Zhang MZ, Harris RC.   +11 more
europepmc   +1 more source

Ergosta-4,6,8(14),22-tetraen-3-one isolated from Polyporus umbellatus prevents early renal injury in aristolochic acid-induced nephropathy rats

, 2011
Objectives Aristolochic acid (AA) nephropathy, first reported as Chinese herbs nephropathy, is a rapidly progressive tubulointerstitial nephropathy that results in severe anemia, interstitial fibrosis and end-stage renal disease ...
Xiao-Hong Cheng, Wen-Ji Sun, Rui-Chao Lin, Jia-Rong Mao, Ying-Yong Zhao, Li Zhang, Yongmin Zhang   +6 more
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Ultrasound enhances the therapeutic potential of mesenchymal stem cells wrapped in greater omentum for aristolochic acid nephropathy. [PDF]

Stem Cell Res Ther, 2021
Yang Y, Geng X, Chi K, Liu C, Liu R, Chen X, Hong Q, Cai G.   +7 more
europepmc   +1 more source

Study on metabolism of plant carcinogen aristolochic acid I

, 2019
Aristolochic acids (AA) are natural compounds present in plant species of Aristolochiaceae. These plant alkaloids exhibit nephrotoxic effects and are human carcinogens.
Dedíková, Alena
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