Results 41 to 50 of about 44,670 (231)

The breasts of Tutankhamun

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Despite being an obscure pharaoh who ruled for a very short time, Tutankhamun, the boy king, has reigned popular consciousness since the discovery of his tomb in 1922. To endocrinologists, the depiction of the kings of the 18 th dynasty in an androgynous
Krishna G Seshadri
doaj   +1 more source

Skeletal Editing from Pyridine to Aniline via C‐Insertion and N‐Isomerization

open access: yesChemistryEurope, EarlyView.
A concise protocol is presented that converts pyridines into anilines by externalizing the original pyridine nitrogen at either the "ipso" or "ortho" position, which results in para or meta‐primary aniline products. A key carbene‐insertion step precedes nitrogen migration, preserving both ring size and overall structure.
Yun Luo   +3 more
wiley   +1 more source

Correlating Changes in Follicular VLDL Binding and Follicular Aromatase Activity in the Ovulation Cycle of the Laying Hen

open access: yesThe Journal of Poultry Science, 2002
We examined whether very low-density lipoprotein receptors (VLDLR) on the oocyte membrane contributed to changes in VLDL uptake into the yolk by the ovarian follicle during the ovulation cycle of the laying hen.
Taisuke Baba   +4 more
doaj   +1 more source

Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri   +10 more
wiley   +1 more source

Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue

open access: yesBiochemistry and Biophysics Reports
The estrogen-synthesizing enzyme aromatase is expressed in adipose tissue where it controls the local concentration of estrogen. It has been suggested that the organic solvents ethanol and ethylene glycol can induce estrogen synthesis by inhibiting PPARγ
Jacob Ardenkjær-Skinnerup   +9 more
doaj   +1 more source

Regulation of aromatase expression in the anterior amygdala of the developing mouse brain depends on ERβ and sex chromosome complement

open access: yesScientific Reports, 2017
During development sex differences in aromatase expression in limbic regions of mouse brain depend on sex chromosome factors. Genes on the sex chromosomes may affect the hormonal regulation of aromatase expression and this study was undertaken to explore
Carla Daniela Cisternas   +4 more
doaj   +1 more source

Normogonadotropic ovarian insufficiency in adolescence (review of literature and clinical case)

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2017
The objective of the review. Analysis of literature data related to the normogonadotropic ovarian insufficiency. Basic statements. The article presents a literature review and clinical case of normogonadotropic ovarian insufficiency in girls aged 16 ...
T.V. Sorokman   +3 more
doaj   +1 more source

New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity

open access: yesMolecules, 2023
A novel series of 1,2,3-triazole/1,2,4-triazole hybrids 5a, 5b, and 6a–i was designed and synthesized as antiproliferative agents targeting aromatase enzymes.
Mohamed T-E Maghraby   +5 more
doaj   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes

open access: yesFrontiers in Pharmacology, 2023
Introduction: The activation of the P2X7 receptor subtype (P2X7R) has a main role in orchestrating the cellular inflammatory response in many different tissues.
Angelo Di Vincenzo   +4 more
doaj   +1 more source

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