Results 181 to 190 of about 31,759 (252)

Intrinsic conformational equilibria position arrestin-2 for activation. [PDF]

Protein Sci
Shriver TJ, Kahraman K, Pan M, Dağ Ç, Tonelli M, Robson SA, Ziarek JJ.   +6 more
europepmc   +1 more source

Structure-Activity Relationships and Ligand-Dependent Arrestin Bias in μ-Opioid Receptor-Mediated ERK Activation. [PDF]

Biomol Ther (Seoul)
Huang L, Wang M, Kundu D, Paudel S, Peng L, Xian X, Jang CG, Kim KM.   +7 more
europepmc   +1 more source

Newly Developed Mimetic Peptides for Angiotensin II Type 1 Receptor Attenuate Doxorubicin-Induced c-Jun N-Terminal Kinase Activation, a Marker of Pro-Apoptotic Stress Signaling. [PDF]

Biomedicines
Matsuo Y, Suematsu Y, Miura SI.
europepmc   +1 more source

SASH1 as a Context-Dependent Multi-Docking Scaffold Linking Receptor Signaling to Cytoskeletal Dynamics. [PDF]

Int J Mol Sci
Clements CM, Roney MSI, Shellman YG.
europepmc   +1 more source

Mechanistic insight into signal bias by the agonist-dependent conformational dynamics of GPR84. [PDF]

Nat Commun
Suzuki S, Tran DP, Nishikawa K, Kitao A, Fujiyoshi Y.   +4 more
europepmc   +1 more source

Next-Generation GLP-1 Agonist Bioassays: Integrating Precision with Biological Relevance. [PDF]

Int J Mol Sci
Graf C, Reuter J, Rüggeberg S, Mohr S, Petri J, Gelinas S, Niederhaus B, Werner U, Strebe N, Zein ZE, Usener D.   +10 more
europepmc   +1 more source

Structural dynamics of kappa opioid receptor interactions with β-arrestin 1. [PDF]

Nat Commun
Han J, Fine EJ, Jiang Q, Zhuang Y, Suomivuori CM, Chen ZW, Denn E, Whiddon K, Li K, Evers AS, Fuller J, Carter J, Fay JF, Chen M, Dror RO, Che T.   +15 more
europepmc   +1 more source

G protein-coupled receptor kinase 3 couples atypical chemokine receptor 4 independent of G proteins. [PDF]

Mol Pharmacol
Lamme TD, Sánchez Arroyo IB, Smit MJ, Schafer CT.   +3 more
europepmc   +1 more source

Agonist-specific conformational dynamics at the β₂-adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation. [PDF]

Br J Pharmacol
Shah SD, Richard J, Ghosh S, Jerwick J, Gavali JT, Penn RB, MacKerell AD, Deshpande DA.   +7 more
europepmc   +1 more source

Virtual Screening, Synthesis and In Vitro Characterization of Histamine H₄ Receptor Ligands Based on Pyrimidine Scaffolds. [PDF]

Int J Mol Sci
Michalak O, Cybulski M, Krzeczyński P, Zegrocka-Stendel O, Dutkiewicz M, Dymkowska D, Olejarz-Maciej A, Karcz T, Dubiel M, Mehta P, Kubiszewski M, Lorkowski M, Jakowiecki J, Pasznik P, Miszta P, Stark H, Koziak K, Filipek S.   +17 more
europepmc   +1 more source