Results 191 to 200 of about 46,183 (248)

A µ-opioid receptor superagonist analgesic with minimal adverse effects. [PDF]

Nature
Gomez JL, Ventriglia EN, Frangos ZJ, Sulima A, Robertson MJ, Sacco MD, Budinich RC, Giosan IM, Xie T, Solis O, Tischer AE, Bossert JM, Caldwell KE, Bonbrest H, Essmann A, Garçon-Poca ZM, Choi S, Noya MR, Limiac F, Arce A, Glatfelter GC, Robinson M, Chen L, Mullarkey AA, Brademan DR, Enten G, Dunne W, Quiroz C, Schoenborn I, Lee CB, Rais R, Holt DP, Dannals RF, Shi L, Hüttenhain R, Ferré S, Kiyatkin E, Bonaventura J, Shaham Y, Zachariou V, Baumann MH, Skiniotis G, Rice KC, Michaelides M.   +43 more
europepmc   +1 more source

Free fatty acid receptor 2 allosterism is defined by cellular context. [PDF]

Cell Commun Signal
Lind S, Abdi Ali A, Al Hamoud Al Asswad S, Lauschke VM, Forsman H, Dahlgren C, Johansson LC.   +6 more
europepmc   +1 more source

GPCR systems coordinate cellular resilience against aging-associated stress. [PDF]

Front Mol Biosci
Boeringer T, Pardo M, Craig CJ, Gutierrez AN, Duckett DR, McDonald P, Maudsley S.   +6 more
europepmc   +1 more source

Correction: Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

Elife
Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li M, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP.   +27 more
europepmc   +1 more source

Expression of Concern.

Neuroimmunomodulation
europepmc   +1 more source

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Arrestins in Bone

2013
Parathyroid hormone (PTH) is the principle regulator of calcium-phosphorus metabolism and bone turnover. Because of its central role in bone remodeling, recombinant human PTH (i.e., Forteo®; PTH(1-34)) has been developed for the treatment of osteoporosis.
Brittany N, Bohinc, Diane, Gesty-Palmer
openaire   +2 more sources

Diversity in arrestin function

Cellular and Molecular Life Sciences, 2009
The termination of heptahelical receptor signaling is a multilevel process coordinated, in large part, by members of the arrestin family of proteins. Arrestin binding to agonist-occupied receptors promotes desensitization by interrupting receptor-G protein coupling, while simultaneously recruiting machinery for receptor endocytosis, vesicular ...
Ryan T, Kendall, Louis M, Luttrell
openaire   +2 more sources

Phosphorylation-dependent conformational changes of arrestin in the rhodopsin–arrestin complex

Physical Chemistry Chemical Physics, 2020
Conformations of GPCR-bound arrestin depend on the phosphorylation patterns of the GPCR C-loop.
Dali Wang, Xiangdong Liu, Jianqiang Liu, Chen Song   +3 more
openaire   +2 more sources

Arrestins lie in wait

Science Signaling, 2023
Preassociation of β-arrestins with the plasma membrane facilitates their interactions with GPCRs.
openaire   +2 more sources