Results 11 to 20 of about 27,706 (210)

Quality Assessment of Artemether-Lumefantrine Samples and Artemether Injections Sold in the Cape Coast Metropolis [PDF]

Journal of Tropical Medicine, 2016
Most prescribers and patients in Ghana now opt for the relatively expensive artemether/lumefantrine rather than artesunate-amodiaquine due to undesirable side effects in the treatment of uncomplicated malaria.
James Prah, Elvis Ofori Ameyaw, Richmond Afoakwah, Patrick Fiawoyife, Ernest Oppong-Danquah, Johnson Nyarko Boampong   +5 more
doaj   +2 more sources

Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine [PDF]

Malaria Journal, 2010
Background Artemether-lumefantrine is one of the most widely used anti-malarial drug combinations in the world with excellent tolerability and cure rates in adult and paediatric patients with uncomplicated falciparum malaria. The aim of this study was to
Tarning Joel, Najmi Muzammil H, Ali Shabana, Lindegardh Niklas   +3 more
doaj   +2 more sources

Potential Antimalarial Activity of Artemether/Lumefantrine/Doxycycline: A Study in Mice Infected with Plasmodium berghei

Biology, Medicine & Natural Product Chemistry, 2022
Antimalarial drug resistance is one of the greatest challenges towards eradicating malaria. Exploring new combination therapies can overcome resistance challenges.
Udeme Owunari Georgewill, Elias Adikwu
doaj   +1 more source

Pharmacokinetic and Pharmacodynamic Characteristics of a new Pediatric Formulation of Artemether-Lumefantrine in African Children with Uncomplicated Plasmodium Falciparum Malaria. [PDF]

, 2011
The pharmacokinetic and pharmacodynamic properties of a new pediatric formulation of artemether-lumefantrine, dispersible tablet, were determined within the context of a multicenter, randomized, parallel-group study.
Lyimo, John, Tekete, Mamadou, Abdulla, Salim, Salim Abdulla, Bassat, Quique, Abdoulaye A. Djimdé, Mandomando, Inacio, Gilbert Lefèvre, Lefèvre, Gilbert, null null, Djimdé, Abdoulaye A, Mamadou Tekete, Borrmann, Steffen, John Lyimo, Quique Bassat, Steffen Borrmann, Inacio Mandomando   +16 more
core   +1 more source

Malaria-Associated Secondary Hematophagocytic Lymphohistocytosis-A Case Report and Comprehensive Literature Review (sHLH). [PDF]

Clin Case Rep
ABSTRACT Malaria‐associated secondary HLH, though rare, is often overlooked. Clinicians should maintain a high‐index of suspicion in travelers returning from malaria‐endemic regions who develop severe to rapidly worsening inflammatory illness, as early recognition is critical for survival.
Yadav I, Jha SK, Singh S, Mandal DK, Jha S.   +4 more
europepmc   +2 more sources

Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]

, 2010
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Färnert, Anna, Zul Premji, Mårtensson, A, Annerberg, A, Mårtensson, Andreas, Annerberg, A., Andreas Mårtensson, Martensson, A., Bjorkman, A., Ngasala, B., Lindegårdh, N, Hietala, Sofia Friberg, Ngasala, B, Ashton, M., Dahlström, S, Gil, P, Friberg Hietala, Sofia,, Björkman, A, Premji, Z., Björkman, Anders, Sofia Friberg Hietala, Premji, Zul, Farnert, A., Dahlström, Sabina, Hietala, SF, Anna Annerberg, Annerberg, Anna, Anders Björkman, Anna Färnert, Pedro Gil, Lindegårdh, Niklas, Ashton, M, Ngasala, Billy, Michael Ashton, Färnert, A, Niklas Lindegårdh, Dahlstrom, S., Gil, P., Billy Ngasala, Lindegardh, N., Ashton, Michael, Gil, J. P., Premji, Z, Gil, Pedro, Hietala, S.F., Ashton, Michael,, Sabina Dahlström   +46 more
core   +1 more source

Solidification of Self-Emulsifying Drug Delivery Systems as a Novel Approach to the Management of Uncomplicated Malaria

Pharmaceuticals, 2022
Malaria affects millions of people annually, especially in third-world countries. The mainstay of treatment is oral anti-malarial drugs and vaccination. An increase in resistant strains of malaria parasites to most of the current anti-malarial drugs adds
Eun Bin Seo, Lissinda H. du Plessis, Joe M. Viljoen   +2 more
doaj   +1 more source

Artesunate: The Best Drug in the Treatment of Severe and Complicated Malaria

Pharmaceuticals, 2010
This review summarizes progress in treating severe and complicated malaria, which are global problems, claiming at least one million lives annually, and have been accompanied by advances in our understanding of the pathogenesis of severe malaria ...
Qigui Li, Peter Weina
doaj   +1 more source

Antidiabetic Effect of Artemether in Db/Db Mice Involves Regulation of AMPK and PI3K/Akt Pathways

Frontiers in Endocrinology, 2020
The traditional Chinese medicine has long been used in the treatment of diabetes, one major disease threatening the public health. It has been reported that artemether exerts antidiabetic effects on type 2 diabetes in db/db mice, however the underlying ...
Xiaolin Bai, Ruixia Pei, Wen Lei, Meiyun Zhao, Jialin Zhang, Lu Tian, Junke Shang   +6 more
doaj   +1 more source

α-Artemether [PDF]

Acta Crystallographica Section E Structure Reports Online, 2007
The title compound, C16H26O5, a derivative of the anti­malaria compound artesunate, consists primarily of three substituted ring systems fused together. A cyclo­hexane ring (distorted chair configuration) fused to a tetra­hydro­pyran group (normal chair) is adjacent to an oxacyclo­heptane unit containing an endoperoxide bridge, giving the mol­ecule a ...
Butcher, Ray J., Jasinski, Jerry P., Yathirajan, H. S., Bindya, S., Narayana, B.   +4 more
openaire   +2 more sources