Results 31 to 40 of about 28,065 (211)

Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda. [PDF]

, 2006
BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutrition, and a lack ...
Bajunirwe, Francis, Piola, P, Piola, Patrice, Taylor, W R J, Babigumira, J, Kyomuhendo, J, Taylor, Walter R. J., Checchi, Francesco, Babigumira, Joseph, Ruzagira, E, Kyomuhendo, Juliet, Taylor, Walter RJ, Ferradini, Laurent, Kiguli, James, Kiguli, J, Ferradini, L, Fogg, C, Fogg, Carole, Bajunirwe, F, Guthmann, J P, Ruzagira, Eugene, Biraro, S, Kigozi, Isaac, Checchi, F, Guthmann, Jean-Paul, Biraro, Samuel, Grandesso, Francesco, Grandesso, F, Kigozi, I, Kyomuhendo Juliet, Laurent Ferradini, Francis Bajunirwe, Walter RJ Taylor, Carole Fogg, Eugene Ruzagira, Isaac Kigozi, Taylor Walter RJ, Ruzagira Eugene, Biraro Samuel, Piola Patrice, Fogg Carole, Francesco Checchi, Samuel Biraro, Babigumira Joseph, Kigozi Isaac, James Kiguli, Grandesso Francesco, Joseph Babigumira, Kiguli James, Jean-Paul Guthmann, Ferradini Laurent, Patrice Piola, Guthmann Jean-Paul, Francesco Grandesso, Checchi Francesco, Juliet Kyomuhendo, Bajunirwe Francis   +56 more
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Optimizing derivatization conditions using an experimental design and simultaneous estimation of artemether and lumefantrine by ratio first order derivative spectrophotometric method

Journal of Taibah University for Science, 2017
Artemether–lumefantrine is the most widely used artemisinin-based combination therapy for malaria. The present work aims to develop and validate a simple, accurate, precise and rapid ratio first order derivative spectrophotometric method for the ...
Jenee Christian, Purvi Shah, Margi Patel, Kalpana Patel, Tejal Gandhi   +4 more
doaj   +1 more source

Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis

Parasites & Vectors, 2011
Background Praziquantel has been used as first-line drug for chemotherapy of schistosomiasis since 1984. Besides praziquantel, artemether and artesunate have also been used for the control of this infectious disease since late 1990s.
Zhao Qin-Ping, Guo Yi, Dong Hui-Fen, Liu Rong, Jiang Ming-Sen   +4 more
doaj   +1 more source

New Uses for Old Drugs: The Tale of Artemisinin Derivatives in the Elimination of Schistosomiasis Japonica in China

Molecules, 2014
Artemisinin (qinghaosu), extracted from the Chinese herb Artemisia annua L. in 1972, and its three major derivatives—artemether, artesunate and dihydroartemisinin—were firstly identified as antimalarials and found active against all species of the ...
Yi-Xin Liu, Wei Wu, Yue-Jin Liang, Zu-Liang Jie, Hui Wang, Wei Wang, Yi-Xin Huang   +6 more
doaj   +1 more source

Artemether-lumefentrine vs quinine in cerebral malaria.pdf

, 2016
Quinine by exploring its effectiveness in cerebral malaria in hospitalized patients. Materials and Methods: A randomized prospective study was conducted among 64 hospitalized cases of cerebral malaria.
AHMED TANJIMUL ISLAM (Tanjim Ovee) (3234204)
core   +1 more source

Implementation of artemether-lumefantrine treatment policy for malaria at health facilities in Tanzania [PDF]

, 2011
V Mugoyela1, O Minzi21Department of Medicinal Chemistry, 2Unit of Pharmacology and Therapeutics, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, TanzaniaBackground: The purpose of this study was to compare knowledge
Mugoyela V, Minzi 0, Veronica Mugoyela, Omary Minzi   +3 more
core   +1 more source

Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial. [PDF]

, 2007
OBJECTIVES: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. DESIGN: Randomized single-blinded clinical trial.
Staedke Sarah G, Yeka Adoke, Dorsey, Grant, Rwakimari John B, Nosten François, Talisuna, Ambrose O, Dorsey Grant, Greenhouse Bryan, Rosenthal Philip J, Lugemwa, Myers, Rosenthal, Philip J, Yeka, Adoke, Staedke, Sarah G, Greenhouse, Bryan, Rwakimari, John B, Bukirwa, Hasifa, Kamya Moses R, Lugemwa Myers, Kamya, Moses R, Bukirwa Hasifa, Wabwire-Mangen Fred, Talisuna Ambrose O, Wabwire-Mangen, Fred, Nosten, François   +23 more
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Ultrastructural alterations in adult Schistosoma mansoni caused by artemether

Memorias do Instituto Oswaldo Cruz, 2002
Progress has been made over the last decade with the development and clinical use of artemether as an agent against major human schistosome parasites.
Shuhua Xiao, Binggui Shen, Jürg Utzinger, Jacques Chollet, Marcel Tanner   +4 more
doaj   +1 more source

Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics

Frontiers in Pharmacology
BackgroundDiabetes mellitus (DM) is a metabolic disease with high morbidity, which significantly affects human life and health expenditures. Previous studies have demonstrated that artemether (ATM) has anti-diabetes and anti-inflammation activities, but ...
Tao Jiang, Peipei Du, Dongxia Liu, Hetao Chen, Yujin Ma, Bin Hu, Jingna Li, Hongwei Jiang, Xuejiao Li   +8 more
doaj   +1 more source

Antimalarial Drugs Enhance the Cytotoxicity of 5-Aminolevulinic Acid-Based Photodynamic Therapy against the Mammary Tumor Cells of Mice In Vitro

Molecules, 2019
Artemisinin and its derivatives, including artesunate (ART) and artemether (ARM), exert anticancer effects in the micromolar range in drug and radiation-resistant cell lines.
Tomohiro Osaki, Kiwamu Takahashi, Masahiro Ishizuka, Tohru Tanaka, Yoshiharu Okamoto   +4 more
doaj   +1 more source