Results 51 to 60 of about 28,065 (211)

A REVIEW OF CLINICAL STUDIES OF ANTICANCER ACTIVITY OF ARTEMISININ DERIVATIVE

Фармация и фармакология (Пятигорск), 2018
Artemisinin is a sesquiterpene lactone isolated from the aerial part of sweet wormwood (Artemisia annua L.) in the 1970s. Based on its derivatives, the most effective medicines for the treatment of malaria have been created and are widely used.
D. A. Konovalov, A. A. Khamilonov, O. M. Shevchuk, L. A. Logvinenko   +3 more
doaj   +1 more source

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, Volume 2, Issue 3, September 2026.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra, Xue‐Jiao Wang, Ka Diam Go, Li Feng, Miaomiao Cai, Guang‐Lei Ma, Clarissa Widyantoro, Lik Tong Tan, Zbynek Bozdech, Zhe Wang, Zhao‐Xun Liang   +10 more
wiley   +2 more sources

Audit of failure rate of Coartem to treat falciparum malaria at single fourteen day follow up

South African Family Practice, 2002
Objective: To assess the failure rate of the new first line treatment regime for uncomplicated falciparum malaria in KwaZulu-Natal of Coartem tablets (20mg aftemether and 120mg lumefantrine - Novartis South Africa (PTY Ltd. Design: A before-after study.
C.H. Vaughan Williams, C. La Cock, G.F.J. Henry, A.J. Ross   +3 more
doaj   +1 more source

Age‐Related and Seasonal Variation in Malaria and Other Causes of Fever and Their Association With Clinical Outcomes in Southern Angola: A Hospital‐Based Study

Tropical Medicine &International Health, Volume 31, Issue 9, Page 1273-1283, September 2026.
ABSTRACT Background Acute febrile illnesses in sub‐Saharan Africa are often attributed to malaria, yet many patients test negative for malaria parasites. The aetiology of nonmalarial fevers remains understudied. Here, we examine likely causes of febrile illnesses and their association with poor clinical outcomes in Angola.
Helga E. M. Gonçalves, Maria Lina Antunes, Jorge Seixas, Marcelo U. Ferreira   +3 more
wiley   +1 more source

Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A Randomized Trial-1

, 2011
Copyright information:Taken from "Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A Randomized Trial"PLoS Clinical Trials 2007;2(5):-.Published online 18 May 2007PMCID:PMC1876597. © 2007 Kamya et al.
Moses R Kamya (18018), Myers Lugemwa (74818), John B Rwakimari (74819), Sarah G Staedke (18026), Fred Wabwire-Mangen (18024), Hasifa Bukirwa (18016), Ambrose O Talisuna (51375), Bryan Greenhouse (74820), François Nosten (17237), Adoke Yeka (18017), Grant Dorsey (18025), Philip J Rosenthal (18023)   +11 more
core   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, Volume 13, Issue 47, 24 August 2026.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A Randomized Trial-0

, 2011
Copyright information:Taken from "Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Malaria: A Randomized Trial"PLoS Clinical Trials 2007;2(5):-.Published online 18 May 2007PMCID:PMC1876597. © 2007 Kamya et al.
Moses R Kamya (18018), Myers Lugemwa (74818), John B Rwakimari (74819), Sarah G Staedke (18026), Fred Wabwire-Mangen (18024), Hasifa Bukirwa (18016), Ambrose O Talisuna (51375), Bryan Greenhouse (74820), François Nosten (17237), Adoke Yeka (18017), Grant Dorsey (18025), Philip J Rosenthal (18023)   +11 more
core   +1 more source

Green Chiral HPLC Method for Lumefantrine Analysis: Method Development, Greenness Assessment, and Computational Studies

Chirality, Volume 38, Issue 8, August 2026.
A green chiral HPLC method was developed and validated for the determination of lumefantrine enantiomers. The method employs ethanol as a mobile phase as a sustainable and efficient alternative to hexane. The chiral recognition mechanism and elution order of the enantiomers were investigated using electronic circular dichroism and molecular docking ...
Amanda Mohr, Gustavo Machado das Neves, Érika Segala, Vera Lucia Eifler‐Lima, Martin Steppe   +4 more
wiley   +1 more source

MALARIA IN PEDIATRIC AGE GROUP: A STUDY OF 200 CASES

Pakistan Armed Forces Medical Journal, 2018
and resistance to various drugs in children. Design: Descriptive observational Place and duration of study: From 1st April 2002 to 31st March 2004 at Department of Pediatrics, CMH Attock. Material and methods: Children upto 12 years of age with
Muhammad Musarrat Jamal, Jehan Ara, Nadir Ali   +2 more
doaj   +2 more sources