Results 71 to 80 of about 28,065 (211)
Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions
MedComm, Volume 7, Issue 5, May 2026.We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu +8 more
wiley +1 more source
Malaria drug shortages in Kenya: a major failure to provide access to effective treatment. [PDF]
, 2009 A key bench mark of successful therapeutic policy implementation, and thus effectiveness, is that the recommended drugs are available at the point of care.
Kangwana, Beth B +7 more
core +1 more source
A new global strategy for the elimination of schistosomiasis
International Journal of Infectious Diseases, 2017 Mass drug administration utilising a single oral dose of 40 mg/kg of praziquantel (PZQ) has been endorsed and advocated by the World Health Organisation (WHO) for the global control and elimination of schistosomiasis.
Allen G.P. Ross, M.D., Ph.D. +5 more
doaj +1 more source
Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Malaria in pregnancy poses significant risks to the mother, fetus, and neonate, necessitating effective treatment and prevention strategies. This study explored the application of an individualized (‘virtual twin’) physiologically‐based pharmacokinetic (PBPK) modeling approach to the antimalarial drug piperaquine in pregnant women.
Sonia Khier +3 more
wiley +1 more source
, 2021 Artemether, an artemisinin derivative, is used in the management of life-threatening severe malaria. This study aimed to develop an intravenous dosage form of artemether using nanotechnology. Artemether-loaded zein nanoparticles were prepared by modified
Dong, Yuancai +7 more
core +1 more source
ULTRASTRUCTURAL AND MUSCULAR MODIFICATIONS OF ADULT SCHISTOSOMA MANSONI WORMS INDUCED BY ARTEMETHER (ART) IN VITRO [PDF]
Journal of the Egyptian Society of Parasitology, 2018 Schistosomiasis is one of the most important public health problems worldwide. In spite of two decades of safe and effective widespread chemotherapy with praziquantel, the number of individuals with schistosomiasis remains high with the appearance of ...
SALWA ARAFA +5 more
doaj +1 more source
LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA
Journal of Diabetes Investigation, Volume 17, Issue 5, Page 739-750, May 2026.LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang +5 more
wiley +1 more source
Helminthologia, 2020 Biomphalaria alexandrina snails have received much attention due to their great medical importance as vectors for transmitting Schistosoma mansoni infection to humans.
Abdel-Azeem H. H. +3 more
doaj +1 more source
, 2013 (A) U87 cells were treated with artemether (300 µmol/L) and shRNA-VCAM-1 alone or in combination. The apoptosis was evaluated by Annexin V-FITC/PI staining. (B) Statistical analysis. Artemether and shRNA-VCAM-1 significantly promoted the apoptosis of U87
Yi Hu (58993) +7 more
core +1 more source
Effects of artemether on the plasma and urine concentrations of some electrolytes in rats [PDF]
, 2013 This study was carried out to determine the changes in the urine levels of sodium (Na+), potassium (K+), and calcium (Ca2+) of rats during a week of intramuscular administration of artemether (12.5 to 50.0 mg/kg/day), another one week thereafter and ...
Akomolafe, RO +7 more
core +1 more source