Signaling in a polluted world: oxidative stress as an overlooked mechanism linking contaminants to animal communication [PDF]
The capacity to communicate effectively with other individuals plays a critical role in the daily life of an individual and can have important fitness consequences.
Costantini, David, Marasco, Valeria
core +1 more source
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha +4 more
wiley +1 more source
Familial isolated pituitary adenoma is independent of Ahr genotype in a novel mouse model of disease
Human familial isolated pituitary adenoma (FIPA) has been linked to germline heterozygous mutations in the gene encoding the aryl hydrocarbon receptor-interacting protein (AIP, also known as ARA9, XAP2, FKBP16, or FKBP37).
Anna L. Shen +5 more
doaj +1 more source
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context [PDF]
The aryl hydrocarbon receptor (AhR) mediates the induction of a variety of xenobiotic metabolism genes. Activation of the AhR occurs through binding to a group of structurally diverse compounds, most notably dioxins, which are exogenous ligands ...
BALBONI, GIANFRANCO +10 more
core +1 more source
ABSTRACT The design of lighting systems, has, in recent years, transcended the basic function of providing visibility, becoming a key component of promoting the health and well‐being of occupants by integrating biological, psychological, and energy aspects. The growing understanding of the effects of light on the circadian cycle has posed a fundamental
Lara Vélez González +3 more
wiley +1 more source
Aryl hydrocarbon receptor nuclear translocator in human liver is regulated by miR-24
Aryl hydrocarbon receptor nuclear translocator (ARNT) forms a heterodimer with aryl hydrocarbon receptor or hypoxia inducible factor 1α to mediate biological responses to xenobiotic exposure and hypoxia. Although the regulation mechanism of the ARNT expression is largely unknown, earlier studies reported that the human ARNT protein level was decreased ...
Yuki, Oda +6 more
openaire +2 more sources
A tripartite of immune-, epithelial-, and nervous-systems in the homeostatic regulation of the gut [PDF]
Various cell types in the intestinal mucosa are constantly exposed to complex signals emanating from the lumen, including the microbiota and its metabolites.
Chng, Song Hui
core +1 more source
Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation
Tregs control immune tolerance but can also enable tumor escape. Nanomaterials can now expand or stabilize Tregs to treat autoimmunity and support transplantation or conversely disrupt tumor Tregs to boost antitumor immunity. We also discuss unintended Treg modulation by nanoparticles, safety and manufacturing challenges, and future translational ...
Yiyin Chen +10 more
wiley +1 more source
2,3,7,8-TETRAKLORODIBENZO-P-DIOKSIN (TCDD) MEMACU AKTIVITAS BIOSINTESIS PROTEIN DI JARINGAN PALATUM EMBRIO MENCIT [PDF]
Bahan pencemar dioksin 2,3,7,8-Tetraklorodibenzo-p-dioksin (TCDD) yang diberikan pada mencit bunting menyebabkan janin yang dihasilkan menderita cacat cleft palate, dengan ciri bilah palatum kerdil atau bilah palatum tumbuh pendek.
M., Sagi +3 more
core
Development of the neurohypophysis: A major neuroendocrine interface
Abstract The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypophysis, providing a model system for studying principles in neuroendocrine interface morphogenesis.
Athul R. Ramesh +5 more
wiley +1 more source

