Results 71 to 80 of about 13,476,144 (183)

Structures and functions of insect arylalkylamine N-acetyltransferase (iaaNAT); a key enzyme for physiological and behavioral switch in arthropods

Frontiers in Physiology, 2015
The evolution of N-acetyltransfeases (NATs) seems complex. Vertebrate arylalkylamine N-acetyltransferase (aaNAT) has been extensively studied since it Leads to the synthesis of melatonin, a multifunctional neurohormone prevalent in photoreceptor cells ...
Susumu eHiragaki, Takeshi eSuzuki, Ahmed A. M. eMohamed, Makio eTakeda   +3 more
doaj   +1 more source

Sexually dimorphic traits are associated with subsistence strategy in African faces from the Sahel/Savannah belt

American Journal of Human Biology, Volume 36, Issue 4, April 2024.
Abstract Objectives Previous research revealed that in some African populations, food‐production strategies are associated with facial shape. Nomadic pastoralists living in the African Sahel/Savannah belt have a different facial morphology than their sedentary neighbors. We investigated whether the lifestyle associated with a subsistence pattern has an
Karel Kleisner, Šimon Pokorný, Viktor Černý   +2 more
wiley   +1 more source

New spectrophotometric and radiochemical assays for acetyl-CoA: Arylamine N-acetyltransferase applicable to a variety of arylamines [PDF]

, 1984
Simple and sensitive spectrophotometric and radiochemical procedures are described for the assay of acetyl-CoA:arylamine N-acetyltransferase (NAT; EC 2.3.1.5), which catalyzes the reaction acetyl-CoA + arylamine --> N-acetylated arylamine + CoASH. The
Susan M. Szabo, Andres, Herbert H., Antje J. U-em, W. Weber, Wendell, Szabo, Susan M., Herbert H. Andre, Klem, Antje J., Weber, Wendell W.   +8 more
core   +1 more source

Leukocytoclastic vasculitis caused by sulfamethoxazole‐trimethoprim

Clinical Case Reports, Volume 12, Issue 2, February 2024.
Violaceous round papules and a surrounding rim of macular purpura coalescing into plaques on both feet 8 days after starting sulfamethoxazole‐trimethoprim. Key Clinical Message Leukocytoclastic vasculitis is a rare, small‐vessel vasculitis that can be caused by sulfamethoxazole‐trimethoprim.
Parjanya Bhatt, Nadine Montreuil, Ayoola Olayiwola, Tanya Quiroz, Felipe Ruiz, Folusakin Ayoade   +5 more
wiley   +1 more source

Arylamine N-Acetyltransferases in Anthropology

, 2018
Abstract Among the many genes involved in the metabolism of therapeutic drugs, human arylamine N-acetyltransferases (NATs) genes have been extensively studied, due to their medical importance both in pharmacogenetics and disease epidemiology. One member of this small gene family, NAT2, is established as the locus of the classic human acetylation ...
Sabbagh, Audrey, Darlu, Pierre, Vangenot, Christelle, Poloni, Estella S.   +3 more
openaire   +4 more sources

Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine N-Acetyltransferase 1, a Potential Breast Cancer Biomarker

, 2016
Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine N-Acetyltransferase 1, a Potential Breast Cancer ...
Ai M. Fletcher (1310784), Matthew H. J. Crawford (2311609), Akane Kawamura (50084), Isaac M. Westwood (106473), Edith Sim (50087), Angela J. Russell (106482), Nicola Laurieri (441488), Stephen G. Davies (106481), James Robinson (5641)   +8 more
core   +1 more source

Estimation of N-acetyltransferase 2 haplotypes [PDF]

N-Acetyltransferase 2 (NAT2) genotyping may result in a considerable percentage in several ambiguous allele combinations. PHASE 2.1 is a statistical program which is designed to estimate the probability of different allele combinations.
Golka, Klaus, Bolt, Hermann M., Selinski, Silvia, Dannappel, Doris, Blaszkewicz, Meinolf, Samimi, Mirabutaleb   +5 more
core  

Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine N-Acetyltransferase 1, a Potential Breast Cancer Biomarker

, 2010
The identification, synthesis, and evaluation of a series of naphthoquinone derivatives as selective inhibitors of human arylamine N-acetyltransferase 1 and mouse arylamine N-acetyltransferase 2 are described.
Fletcher, Ai M., Russell, AJ, Kawamura, A, Sim, E, Russell, Angela J., Crawford, Matthew H. J., Crawford, MH, Westwood, IM, Davies, SG, Robinson, J, Laurieri, N, Westwood, Isaac M., Laurieri, Nicola, Sim, Edith, Kawamura, Akane, Davies, Stephen G., Fletcher, AM, Davies, Stephen, Robinson, James   +18 more
core   +1 more source

Role of human arylamine N-acetyltransferase in carcinogen metabolism and human breast cancer progression. [PDF]

, 2012
Human arylamine N-acetyltransferase (NAT) is a phase II cytosolic enzyme that occurs as two isozymes, NAT1 and NAT2. This family of polymorphic enzymes catalyzes the detoxification and/or activation of many aromatic and heterocyclic amine drugs and ...
Leggett, Carmine Simone
core   +1 more source

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis. [PDF]

Breast Cancer Res Treat, 2022
McAleese CE, Butcher NJ, Minchin RF.
europepmc   +2 more sources