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Astrocyte morphology

open access: yesTrends in Cell Biology, 2023
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal feature of astrocytes is their complex and visually enchanting morphology, referred to as bushy, spongy, and star-like. A central precept of this review is that such complex morphological shapes evolved to allow astrocytes to contact and signal with diverse ...
Baldwin, Katherine T   +2 more
openaire   +5 more sources

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease

open access: yesScience, 2022
Astrocytes, a type of glia, are abundant and morphologically complex cells. Here, we report astrocyte molecular profiles, diversity, and morphology across the mouse central nervous system (CNS).
Fumito Endo   +2 more
exaly   +2 more sources

Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis [PDF]

open access: yesNature, 2017
Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the neuropil and interact with synapses. The mechanisms that control the establishment of astrocyte morphology are unknown, and it is unclear whether impairing astrocytic infiltration of the neuropil alters synaptic connectivity.
Katherine T Baldwin   +2 more
exaly   +3 more sources

Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1 [PDF]

open access: yesCell Reports, 2018
Summary: Circadian clock dysfunction is a common symptom of aging and neurodegenerative diseases, though its impact on brain health is poorly understood. Astrocyte activation occurs in response to diverse insults and plays a critical role in brain health
Brian V. Lananna   +15 more
doaj   +3 more sources

Reactive astrocyte nomenclature, definitions, and future directions

open access: yesNature Neuroscience, 2021
Carole Escartin   +2 more
exaly   +2 more sources

Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer

open access: yesNature, 2016
Brain metastasis represents a substantial source of morbidity and mortality in various cancers, and is characterized by high resistance to chemotherapy.
Adrienne A Boire   +2 more
exaly   +2 more sources

Astrocyte-neuron metabolic cooperation shapes brain activity.

open access: yesCell Metabolism, 2021
The brain has almost no energy reserve, but its activity coordinates organismal function, a burden that requires precise coupling between neurotransmission and energy metabolism.
G. Bonvento, J. Bolaños
semanticscholar   +1 more source

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