Results 21 to 30 of about 283,599 (345)
Scientific Reports, 2022 An emerging link between circadian clock function and neurodegeneration has indicated a critical role for the molecular clock in brain health. We previously reported that deletion of the core circadian clock gene Bmal1 abrogates clock function and ...
Celia A. McKee +5 more
doaj +1 more source
Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. [PDF]
, 2014 Although astrocytes are the most abundant cell type in the central nervous system (CNS), little is known about their molecular specification and differentiation.
Chen, Yidan +10 more
core +3 more sources
Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. [PDF]
PLoS Biology, 2012 Long-term potentiation (LTP) of synaptic transmission represents the cellular basis of learning and memory. Astrocytes have been shown to regulate synaptic transmission and plasticity.
Marta Navarrete +6 more
doaj +1 more source
Astrocyte Reprogramming in Stroke: Opportunities and Challenges
Frontiers in Aging Neuroscience, 2022 Stroke is a major cause of morbidity and mortality worldwide. In the early stages of stroke, irreversible damage to neurons leads to high mortality and disability rates in patients.
Zhouzhou Peng +7 more
doaj +1 more source
Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes
Cells, 2019 Vimentin (VIM) is an intermediate filament (nanofilament) protein expressed in multiple cell types, including astrocytes. Mice with VIM mutations of serine sites phosphorylated during mitosis (VIMSA/SA) show cytokinetic failure in fibroblasts and lens ...
Yolanda de Pablo +6 more
doaj +1 more source
Journal of Neuroinflammation, 2023 Despite extensive astrocyte activation in patients suffering from HIV-associated neurocognitive disorders (HAND), little is known about the contribution of astrocytes to HAND neuropathology.
Jingxian Lun +10 more
doaj +1 more source
Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation [PDF]
, 2018 Neurons require a nearly constant supply of ATP. Glucose is the predominant source of brain ATP, but the direct effects of prolonged glucose deprivation on neuronal viability and function remain unclear.
Mennerick, Steven +3 more
core +3 more sources
Diversity of astrocyte functions and phenotypes in neural circuits
Nature Neuroscience, 2015 Baljit S Khakh, Michael V Sofroniew
exaly +2 more sources
The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway
Frontiers in Medicine, 2019 Background:Toxoplasma gondii is a protozoan parasite that chronically infects nearly one-third of the world's human population. In immunosuppressed individuals and fetus, infection with T.
Yu Jin +6 more
doaj +1 more source
Parkinson's Disease, 2012 Dementia is a common feature in Parkinson’s disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes.
Simone A. van den Berge +3 more
doaj +1 more source