Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. [PDF]
, 2018 Glaucoma is characterized by a progressive loss of retinal ganglion cells and their axons, but the underlying biological basis for the accompanying neurodegeneration is not known.
Bu, Jung Hyun +8 more
core +2 more sources
Novel cell separation method for molecular analysis of neuron-astrocyte cocultures
Frontiers in Cellular Neuroscience, 2014 Over the last decade, the importance of astrocyte-neuron communication in neuronal development and synaptic plasticity has become increasingly clear. Since neuron-astrocyte interactions represent highly dynamic and reciprocal processes, we hypothesized ...
Andrea eGoudriaan +8 more
doaj +1 more source
Effects of 660-nm LED photobiomodulation on drebrin expression pattern and astrocyte migration
Scientific Reports, 2023 Photobiomodulation (PBM) is a therapeutic tool that uses red or near-infrared light in medical applications. It’s applications in both central (CNS) and peripheral nervous system (PNS) are widely studied.
Sung Ryeong Yoon +3 more
doaj +1 more source
Neuron-Astrocyte Associative Memory [PDF]
arXiv, 2023 Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, there are no current theories that explain how neurons, synapses, and astrocytes might collectively contribute to memory function.
arxiv
Non-aggregated Aβ25-35 Upregulates Primary Astrocyte Proliferation In Vitro
Frontiers in Cellular Neuroscience, 2017 Amyloid beta (Aβ) is a peptide cleaved from amyloid precursor protein that contributes to the formation of senile plaques in Alzheimer’s disease (AD). The relationship between Aβ and astrocyte proliferation in AD remains controversial.
Elise C. Ohki +5 more
doaj +1 more source
Tet1 Regulates Astrocyte Development and Cognition of Mice Through Modulating GluA1
Frontiers in Cell and Developmental Biology, 2021 Tet (Ten eleven translocation) family proteins-mediated 5-hydroxymethylcytosine (5hmC) is highly enriched in the neuronal system, and is involved in diverse biological processes and diseases.
Weize Xu +22 more
doaj +1 more source
A Neural-Astrocytic Network Architecture: Astrocytic calcium waves modulate synchronous neuronal activity [PDF]
, 2018 Understanding the role of astrocytes in brain computation is a nascent challenge, promising immense rewards, in terms of new neurobiological knowledge that can be translated into artificial intelligence. In our ongoing effort to identify principles endow-ing the astrocyte with unique functions in brain computation, and translate them into neural ...
arxiv +1 more source
Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation [PDF]
, 2018 Neurons require a nearly constant supply of ATP. Glucose is the predominant source of brain ATP, but the direct effects of prolonged glucose deprivation on neuronal viability and function remain unclear.
Mennerick, Steven +3 more
core +3 more sources
Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma
Frontiers in PharmacologyBackgroundTumor metabolism reprogramming is a hallmark of cancer, but metabolite-mediated intercellular communication remains poorly understood. To address this gap, we estimated and explored communication events exploring based on single‐cell RNA data ...
Qiang Liu +9 more
doaj +1 more source
Biomedicines, 2023 Astrocyte inflammation activation is an important cause that hinders the recovery of motor function after cerebral ischemia. However, its molecular mechanism has not yet been clearly clarified.
Doudou Luo +7 more
doaj +1 more source