Results 51 to 60 of about 108,676 (277)

Computational and Experimental Studies on the α-Functionalization of Ketones Using Domino Reactions: A Strategy to Increase Chemoselectivity at the α-Carbon of Ketones

Molecules
A facile strategy to increase the chemoselectivity of domino reactions was proposed and successfully applied in the α-functionalization of ketones.
Hui Sun, Li-Heng Yang, Meng-Yun Fu, Bin Cui   +3 more
doaj   +1 more source

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]

, 2016
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D., Porco, John A., Stephenson, Corey R.J.   +2 more
core   +2 more sources

Progress in Stereoselective Haloamination of Olefins

Molecules
The regio- and stereoselective adjacent bifunctionalization of olefins with amine and halogen groups can be effectively accomplished through catalytic haloamination methods.
Guo Zhong, Jiayu Zhou, Bin Cui, Hui Sun
doaj   +1 more source

Heterogenisation of ketone catalysts within mesoporous supports for asymmetric epoxidation

, 2013
The synthesis of the first mesoporous silica (150 Å) anchored carbohydrate-derived chiral ketone is described. This new heterogeneous catalyst has been shown to be effective in the asymmetric epoxidation of olefins by oxone.
Adam, Aggarwal, Amadori, Amadori, Armstrong, Beckwith, Bellamy, Bloch, Caprio, Chadwick, Cho, Corey, Denmark, Denmark, Denmark, Dondoni, Farina, Frohn, Goeddel, Heitbaum, Hutchings, Jacobsen, Johansson Seechurn, Johnson, Johnson, Jones, Katsuki, McMorn, Page, Page, Pedragosa-Moreau, Raja, Raynor, Ren, Romesberg, Ross, Sartori, Shephard, Shu, Song, Stearman, Thomas, Thomas, Thomas, Tian, Tian, Tian, van den Broek, Wang, Wang, Wang, Wang, Wong, Wong, Xia, Xiong, Xuereb, Yang, Yang, Zhao, Zhu   +60 more
core   +1 more source

Rational design of a (S)-selective-transaminase for asymmetric synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine [PDF]

, 2016
Amine transaminases offer an environmentally sustainable synthesis route for the production of pure chiral amines. However, their catalytic efficiency toward bulky ketone substrates is greatly limited by steric hindrance and therefore presents a great ...
Allen, Christopher C.R., Brown, Rodney T., Carvalho, Alexandra T.P., Caswell, Jill M., Dheeman, Dharmendra S., Dourado, Daniel F.A.R., Huang, Meilan, Kulakov, Leonid, Miskelly, Iain, Moody, Thomas S., Pohle, Stefan, Quinn, Derek J., Skvortsov, Timofey   +12 more
core   +3 more sources

An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1

Engineering
Vitamin B1 is widely applied in the healthcare and food industry as an antineuritic and antioxidant to maintain the normal functioning of nerve conduction, the heart, and the gastrointestinal tract.
Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fen-Er Chen   +4 more
doaj   +1 more source

Functionalization of Pyrene To Prepare Luminescent Materials—Typical Examples of Synthetic Methodology [PDF]

, 2016
Pyrene-based π-conjugated materials are considered to be an ideal organic electro-luminescence material for application in semiconductor devices, such as organic light-emitting diodes (OLEDs), organic field-effect transistors (OFETs) and organic ...
Ajami, Alfonso, Baldo, Barton, Batsanov, Beaupré, Beller, Bernhardt, Bolm, Cao, Caronna, Caronna, Casas-Solvas, Cerfontain, Chang, Chen, Chen, Cheng, Chercka, Coventry, Crawford, Dewar, Duong, Eliseeva, Espinosa, Feng, Feng, Feng, Feng, Feng, Feng, Feng, Figueira-Duarte, Figueira-Duarte, Figueira-Duarte, Fihri, Fuchibe, Gao, García, Gonell, Grandbois, Hashmi, Hong, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Hu, Ibáñez, Inoue, Irvine, Ito, Iwasaki, Jeon, Ji, Ji, Jiang, Jiao, Kamtekar, Katz, Kawano, Keller, Kim, Kim, King, Klauk, Kohl, Kulisic, Kumar, Lambert, Lee, Lee, Letizia, Li, Li, Liu, Malashikhin, Marco, Mateo-Alonso, Miyasaka, Miyaura, Miyaura, Miyazawa, Miyazawa, Mkhalid, Moorthy, More, More, Moulin, Ni, Niko, Oberender, Olah, Olah, Paul, Qiao, Rajca, Rajca, Rathore, Reineke, Schmidt-Mende, Sonar, Sun, Sun, Szaciłowski, Tan, Tanaka, Tang, Tao, Tashiro, Thomas, Trattnig, Trattnig, Valdés, Venkataramana, Verbiest, Verbiest, Visbal, Vollmann, Xiao, Xu, Yamato, Yamato, Yamato, Yamato, Yamato, Yua, Zak, Zhang, Zhang, Zhao, Zwijnenburg, Zöphel, Zöphel, Zöphel   +139 more
core   +1 more source

Asymmetric Catalysis with Helical Polymers [PDF]

Chemistry – A European Journal, 2011
AbstractInspired by nature, the use of helical biopolymer catalysts has emerged over the last years as a new approach to asymmetric catalysis. In this Concept article the various approaches and designs and their application in asymmetric catalysis will be discussed.
Megens, Rik P., Roelfes, Gerard
openaire   +3 more sources

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase [PDF]

, 2012
Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O2 and H2O2. SOD also reacts with H2O2, leading to the formation of a strong
Luis Eduardo Soares Netto, Michael A. Hough, Richard W. Strange, S. Samar Hasnain, Svetlana V. Antonyuk   +4 more
core   +7 more sources

Insights Into the Carboxyltransferase Reaction of Pyruvate Carboxylase From the Structures of Bound Product and Intermediate Analogs [PDF]

, 2013
Pyruvate carboxylase (PC) is a biotin-dependent enzyme that catalyzes the MgATP- and bicarbonate-dependent carboxylation of pyruvate to oxaloacetate, an important anaplerotic reaction in central metabolism.
Lietzan, Adam D., Maurice, Martin St.
core   +2 more sources