Results 61 to 70 of about 31,425 (239)
Organocatalytic C─O Bond Cleavage and Asymmetric Transformations via [1,3]‐Sigmatropic Rearrangement
Advanced Science, EarlyView.A direct asymmetric strategy for fulfilling the functional group transfer by aryl ether cleavage and migration is developed, representing the first Brønsted base‐catalyzed asymmetric [1,3]‐sigmatropic rearrangement reaction. The resulting chiral benzofuran products generated through this strategy exhibit significant 3D‐dimensionality and demonstrate ...
Lei Peng +7 more
wiley +1 more source
Molecules, 2016 The organocatalysis-based dynamic kinetic resolution (DKR) process has proved to be a powerful strategy for the construction of chiral compounds. In this feature review, we summarized recent progress on the DKR process, which was promoted by chiral ...
Pan Li +3 more
doaj +1 more source
A bifunctional photoaminocatalyst for the alkylation of aldehydes: Design, analysis, and mechanistic studies [PDF]
, 2018 This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Catalysis, copyright ©2018 American Chemical Society after peer review and technical editing by the publisher.
Alemán, José +6 more
core +5 more sources
Asian Journal of Organic Chemistry, EarlyView.The excellent catalytic performance of a BINOL‐derived sulfide catalyst bearing a diphenylmethanol unit was demonstrated in the highly enantioselective synthesis of γ‐butyrolactones via bromolactonization. Abstract A BINOL‐derived sulfide catalyst bearing a diphenylmethanol unit was prepared.
Yasuaki Furuya +2 more
wiley +1 more source
A One-Pot Tandem Strategy in Catalytic Asymmetric Vinylogous Aldol Reaction of Homoallylic Alcohols
Molecules, 2016 Reported is a rationally-designed one-pot sequential strategy that allows homoallylic alcohols to be employed in a catalytic, asymmetric, direct vinylogous aldol reaction with a series of activated acyclic ketones, including trifluoromethyl ketones, γ ...
Xufeng Hou +3 more
doaj +1 more source
Recent progress in the asymmetric Mannich reaction [PDF]
, 2012 The asymmetric Mannich reaction is one of the most useful carbon-carbon bond forming reactions for the synthesis of chiral molecules containing nitrogen.
Bing, Xie, Hui, Guo, Xiao-Hua, Cai
core +1 more source
Angewandte Chemie International Edition, Accepted Article.This study presents a phosgene‐ and isocyanate‐free route for the synthesis of polyurethanes using (R)‐limonene as a bio‐based starting material. The synthesis of the cyclic limonene‐based carbamate monomer LU is achieved in high yields using dimethyl carbonate as a sustainable, less hazardous phosgene surrogate and is verified by NMR, SC‐XRD, ESI‐MS ...
Jonas Futter +4 more
wiley +1 more source
Advances on Greener Asymmetric Synthesis of Antiviral Drugs via Organocatalysis
Pharmaceuticals, 2021 Viral infections cause many severe human diseases, being responsible for remarkably high mortality rates. In this sense, both the academy and the pharmaceutical industry are continuously searching for new compounds with antiviral activity, and in ...
Everton M. da Silva +2 more
doaj +1 more source
Reaction Mechanism of Organocatalytic Michael Addition of Nitromethane to Cinnamaldehyde: A Case Study on Catalyst Regeneration and Solvent Effects [PDF]
, 2017 The Michael addition of nitromethane to cinnamaldehyde has been computationally studied in the absence of a catalyst and the presence of a biotinylated secondary amine by a combined computational and experimental approach. The calculations were performed
Luk, Louis Y. P. +4 more
core +4 more sources
Angewandte Chemie International Edition, Accepted Article.This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley +1 more source