Results 71 to 80 of about 2,455 (178)

Asymmetric Organocatalysis [PDF]

open access: yesAccounts of Chemical Research, 2004
K. N. Houk, Benjamin List
openaire   +1 more source

Enantioselective synthesis of tricyclic amino acid derivatives based on a rigid 4-azatricyclo[5.2.1.02,6]decane skeleton

open access: yesBeilstein Journal of Organic Chemistry, 2009
An enantioselective route to four tricyclic amino acids and N-tosylamides, composed of a central norbornane framework with a 2-endo,3-endo-annelated pyrrolidine ring and a 5-endo-C1 or -C2 side chain, has been developed. A key intermediate was the chiral,
Matthias Breuning   +6 more
doaj   +1 more source

(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis

open access: yesCHIMIA, 2007
This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of
Deborah A. Longbottom   +2 more
doaj   +1 more source

Diastereoselective Synthesis of (–)-Bestatin, Epibestatin, Phebestin and (3S,4R)-4-Amino-3-hydroxy-5-phenylpentanoic Acid from an Aldehyde Derived from d-Phenylalanine

open access: yesSynOpen, 2019
A convenient and efficient method for the synthesis of (–)-bestatin, epibestatin, phebestin, and (3S,4R)-4-amino-3-hydroxy-5-phenylpentanoic acid is reported. The key step is a proline-catalyzed α-hydroxylation of an aldehyde derived from d-phenylalanine,
Vipin Kumar Jain
doaj   +1 more source

Organocatalytic tandem Michael addition reactions: A powerful access to the enantioselective synthesis of functionalized chromenes, thiochromenes and 1,2-dihydroquinolines

open access: yesBeilstein Journal of Organic Chemistry, 2012
Enantioselective organocatalysis has become a field of central importance within asymmetric chemical synthesis and appears to be efficient approach toward the construction of complex chiral molecules from simple achiral materials in one-pot ...
Chittaranjan Bhanja   +3 more
doaj   +1 more source

(Thio)urea-mediated synthesis of functionalized six-membered rings with multiple chiral centers

open access: yesBeilstein Journal of Organic Chemistry, 2016
Organocatalysis, now running its second decade of life, is being considered one of the main tools a synthetic chemist has to perform asymmetric catalysis. In this review the synthesis of six-membered rings, that contain multiple chiral centers, either by
Giorgos Koutoulogenis   +2 more
doaj   +1 more source

Bifunctional primary amine-thioureas in asymmetric organocatalysis

open access: yesOrganic & Biomolecular Chemistry, 2013
Research disclosed since the demonstration of the first examples of primary amine-thiourea organocatalysis in 2006 has shown that primary amine-based thioureas can successfully catalyze a diverse variety of highly enantioselective transformations providing a wide range of versatile organic compounds.
Olga V, Serdyuk   +2 more
openaire   +3 more sources

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