Results 91 to 100 of about 36,768 (197)

Cuticular drusen associated with aneurysmal type 1 neovascularization (polypoidal choroidal vasculopathy)

open access: yesInternational Journal of Retina and Vitreous, 2018
Background Aneurysmal type 1 neovascularization (AT1) is a term recently introduced to better describe the aneurysmal dilatation that may arise from neovascular lesions, more commonly known as polypoidal choroidal vasculopathy.
Serena Fragiotta   +2 more
doaj   +1 more source

Tonoplast‐Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The plant‐derived specialized metabolite montbretin A (MbA) is under development as an improved treatment for Type 2 diabetes, a worldwide epidemic. MbA is an acylated flavonol glycoside so far only found in small amounts in montbretia (Crocosmia × crocosmiiflora) corms.
Charlotte Hijmans   +4 more
wiley   +1 more source

Récepteurs AT1-AT2 de l'angiotensine II et propriétés particulières des antagonistes AT1 sur la circulation cérébrale chez le rat [PDF]

open access: yes, 2012
Le Système Rénine Angiotensine tient une place prépondérante au sein de la circulation cérébrale. Les Antagonistes des Récepteurs AT1 à l'Angiotensine II (ARAII) ont prouvé leur efficacité dans la prévention de l'Accident Vasculaire Cérébral (AVC ...
DUPUIS, François   +2 more
core  

Hypercholesterolemia is associated with enhanced angiotensin AT1-receptor expression

open access: yes, 1997
Low-density lipoprotein increases the AT1-receptor gene expression in vascular smooth muscle cells. To elucidate whether elevated cholesterol serum levels upregulate the AT1 receptor and its functional response to angiotensin II in vivo, we compared 1 ...
K. Strehlow   +6 more
core   +1 more source

Data on necrotic and apoptotic cell death in acute myocardial ischemia/reperfusion injury: the effects of CaMKII and angiotensin AT1 receptor inhibition

open access: yesData in Brief, 2016
Content of particular proteins indicating cellular injury due to apoptosis and necrosis has been investigated in ischemic/reperfused (IR) hearts and ischemic/reperfused hearts treated with CaMKII inhibitor and/or AT1 receptor inhibitor. This data article
Tomas Rajtik   +9 more
doaj   +1 more source

Recent Diachronic Change in Affiliative Vocatives in British English

open access: yesWorld Englishes, EarlyView.
ABSTRACT This study investigates recent diachronic change in affiliative address in spoken British English by comparing data from the demographic components of the BNC1994 and BNC2014. Using a systematically coded dataset of over 6000 vocative tokens, we analyze forms that signal solidarity and social closeness (including dude, bro, girl, dear, love ...
Mariam Gagua   +4 more
wiley   +1 more source

Identification and Characterization of AT1-Antagonists as PPARgamma Ligands

open access: yes, 2005
Titelblatt, Inhaltsverzeichnis und Abkürzungen Einleitung Material und Methoden Ergebnisse Diskussion Zusammenfassung Abstract Literaturverzeichnis Abbildungs- und TabellenverzeichnisDer nukleäre Transkriptionsfaktor Peroxisom ...
Schupp, Michael
core   +1 more source

Early‐stage 2K1C renovascular hypertension does not increase global MHC‐II or F4/80 abundance in the non‐clipped kidney but reveals focal F4/80+ induction

open access: yesExperimental Physiology, EarlyView.
Abstract The two‐kidney, one‐clip (2K1C) model produces renovascular hypertension. The effects on the clipped kidney (CK) are well described, while the non‐clipped kidney (NCK) is used as a model to evaluate the effects of high blood pressure. Although most of these effects have been described at later stages of 2K1C hypertension, it remains unclear ...
Pilar Cárdenas   +11 more
wiley   +1 more source

Angiotensin AT1–Receptor Blockers Enhance Cardiac Responses to Parasympathetic Nerve Stimulation via Presynaptic AT1 Receptors in Pithed Rats

open access: yes, 2013
.: In the present study, we investigated the effects of angiotensin AT1–receptor blockers, KT3-671 and losartan, on the cardiac vagal neurotransmission in pithed rats.
Akane Watanabe   +4 more
core   +1 more source

Factor XIIIA Transglutaminase Crosslinks AT1 Receptor Dimers of Monocytes at the Onset of Atherosclerosis [PDF]

open access: yes, 2004
Many G protein-coupled receptors form dimers in cells. However, underlying mechanisms are barely understood. We report here that intracellular factor XIIIA transglutaminase crosslinks agonist-induced AT1 receptor homodimers via glutamine315 in the ...
Langer, Andreas   +4 more
core   +1 more source

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