Results 151 to 160 of about 106,444 (303)

Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter

Nature Communications
ATP-binding cassette (ABC) transporters use ATP to transport substrates across membranes. In type IV ABC transporters, which include many multidrug resistance (MDR) pumps, communication between nucleotide-binding domains (NBDs) and transmembrane domains (
Victor Hugo Pérez Carrillo, Margot Di Cesare, Dania Rose-Sperling, Waqas Javed, Hannes Neuweiler, Julien Marcoux, Cédric Orelle, Jean-Michel Jault, Ute A. Hellmich   +8 more
doaj   +1 more source

Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates. [PDF]

Open Biol, 2023
Zhang X, Zhao Y, Zheng W, Nan B, Fu J, Qiao Y, Zufall RA, Gao F, Yan Y.   +8 more
europepmc   +1 more source

Drug resistance of hepatoma cells induced by ATP‑binding cassette transporter G2 by reducing intracellular drug concentration. [PDF]

Exp Ther Med, 2023
Li Y, Ding B, Liu J, Li X, He C, Wang J, Liu L.   +6 more
europepmc   +1 more source

The Impact of Polymorphisms in ATP-Binding Cassette Transporter Genes on Anthracycline-Induced Early Cardiotoxicity in Patients with Breast Cancer. [PDF]

J Cardiovasc Dev Dis, 2023
Muckiene G, Vaitiekus D, Zaliaduonyte D, Bartnykaite A, Plisiene J, Zabiela V, Juozaityte E, Jurkevicius R.   +7 more
europepmc   +1 more source

A Novel Type of Fluorescent Chlorophyll Catabolites Hypermodified by Lipophilic Chloroplast Membrane Components

Helvetica Chimica Acta, EarlyView.
Breakdown of chlorophyll (Chl) is a fundamental biological phenomenon. In de‐greening banana leaves, Chl is transformed into colorless “fluorescent” Chl‐catabolites (FCCs) that cause the leaves to luminesce blue. Hypothesis‐driven search for apolar banana‐FCCs, and structure elucidation, have revealed a striking first link between lipid metabolism and ...
Clemens Vergeiner, Bernhard Kräutler
wiley   +1 more source

Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. [PDF]

Mol Cells, 2022
Kim S, Lee SS, Park JG, Kim JW, Ju S, Choi SH, Kim S, Kim NJ, Hong S, Kang JY, Jin MS.   +10 more
europepmc   +1 more source

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

ATP-binding cassette transporter expression is widely dysregulated in frontotemporal dementia with TDP-43 inclusions. [PDF]

Front Mol Neurosci, 2022
Katzeff JS, Lok HC, Bhatia S, Fu Y, Halliday GM, Kim WS.   +5 more
europepmc   +1 more source

The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

Lipids, EarlyView.
ABSTRACT Cardiovascular diseases (CVD) are a leading cause of global mortality, with dyslipidemia playing a central role in their pathogenesis. The influence of alcohol consumption on lipid profiles, particularly high‐density lipoprotein cholesterol (HDL‐c), in relation to obesity status remains insufficiently explored.
Larissa Esthefani Barros Cirino, Divanei Zaniqueli, Oscar Geovanny Enriquez‐Martinez, Camila Maciel de Oliveira, Alexandre da Costa Pereira, Jordana Herzog Siqueira, Rafael de Oliveira Alvim   +6 more
wiley   +1 more source

The role of ATP-binding cassette transporter genes expression in treatment failure cutaneous leishmaniasis. [PDF]

AMB Express, 2022
Boozhmehrani MJ, Eslami G, Khamesipour A, Jafari AA, Vakili M, Hosseini SS, Askari V.   +6 more
europepmc   +1 more source