Results 51 to 60 of about 477 (130)

A randomized placebo-controlled phase I clinical trial to evaluate the immunomodulatory activities of Atractylodes lancea (Thunb) DC. in healthy Thai subjects

BMC Complementary Medicine and Therapies, 2021
Background Atractylodes lancea (Thunb) DC. (AL) and bioactive compounds β-eudesmol and atractylodin have been demonstrated in the in vitro and in vivo studies for their potential clinical use in cholangiocarcinoma.
Inthuon Kulma, Luxsana Panrit, Tullayakorn Plengsuriyakarn, Wanna Chaijaroenkul, Siriprapa Warathumpitak, Kesara Na-Bangchang   +5 more
doaj   +1 more source

Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea.

PLoS ONE, 2019
Rhizomes of Atractylodes lancea are used in traditional Japanese medicine (Kampo) and Chinese medicine to treat numerous diseases and disorders because they contain many pharmacologically active compounds. The major active compounds in A.
Takahiro Tsusaka, Bunsho Makino, Ryo Ohsawa, Hiroshi Ezura   +3 more
doaj   +1 more source

Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study. [PDF]

PLoS ONE, 2015
Rikkunshito, a traditional Japanese (Kampo) medicine, has been used to treat upper gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux.
Hiroyuki Kitagawa, Masaya Munekage, Takashi Matsumoto, Chiharu Sadakane, Miwako Fukutake, Katsuyuki Aoki, Junko Watanabe, Kazuya Maemura, Tomohisa Hattori, Yosio Kase, Yasuhito Uezono, Akio Inui, Kazuhiro Hanazaki   +12 more
doaj   +1 more source

Atractylodin Induces Apoptosis and Inhibits the Migration of A549 Lung Cancer Cells by Regulating ROS-Mediated Signaling Pathways

Molecules, 2022
Atractylodin (ATR) has anticancer effects on some tumor cells by inducing apoptosis, but its mechanism in lung cancer remains unclear. This study investigates the inhibitory effect of ATR on A549 lung cancer cells. Cell viability was detected by the Cell
Tong Zhang, Shu-Mei Li, Yan-Nan Li, Jing-Long Cao, Hui Xue, Chang Wang, Cheng-Hao Jin   +6 more
doaj   +1 more source

Maize intercropping enriches plant growth-promoting rhizobacteria and promotes both the growth and volatile oil concentration of Atractylodes lancea

Frontiers in Plant Science, 2022
In the Atractylodes lancea (A. lancea)-maize intercropping system, maize can promote the growth of A. lancea, but it is unclear whether this constitutes an aboveground or belowground process.
Zheng Peng, Zheng Peng, Xiuzhi Guo, ZengXu Xiang, Dahui Liu, Kun Yu, Kai Sun, Binbin Yan, Sheng Wang, Chuanzhi Kang, Yang Xu, Yang Xu, Hongyang Wang, Tielin Wang, Chaogeng Lyu, Wenjun Xue, Li Feng, Lanping Guo, Yan Zhang, Luqi Huang   +19 more
doaj   +1 more source

Clinical Effectiveness of Rikkunshito in Neonates With Radiologically Confirmed Gastroesophageal Reflux Disease and Gastric Volvulus

Traditional &Kampo Medicine, Volume 13, Issue 1, April 2026.
This retrospective study demonstrates the therapeutic efficacy of Rikkunshito in neonates with radiologically confirmed gastric volvulus or gastroesophageal reflux disease. Rikkunshito treatment significantly improved weight gain and vomiting frequency without serious adverse events, suggesting it is a safe and effective pharmacologic option.
Toshihiro Nakayama, Shonosuke Nara, Naofumi Hanyu, Midori Nishibata, Maria Nishibukuro, Hiroyuki Koga, Takashi Yamazaki, Gaku Yamanaka   +7 more
wiley   +1 more source

Danshensu Ethyl Ester Induces Ferroptosis Through Targeted Inhibition of SLC7A11 Transport Function in NSCLC

Thoracic Cancer, Volume 17, Issue 8, April 2026.
Danshensu ethyl ester (DEE) promotes ferroptosis by targeting and inhibiting the transport function of SLC7A11, independent of the p53 pathway, thereby inhibiting NSCLC. DEE reduces intracellular cysteine and glutathione (GSH) levels, while increasing reactive oxygen species (ROS) and malondialdehyde (MDA), thereby triggering ferroptosis.
Rui Yan, Sen Xu, Meng Yan, Dongyang Wu, Jingwen Zhang, Chunsheng Zhang, Jiale Liu, You‐Jie Li, Jiankai Feng, Gui‐Wu Qu, Shu‐Yang Xie   +10 more
wiley   +1 more source

A Systematic Review on Functional Bioactive Compound Atractylone: Natural Source, Pharmacological Properties and Mechanisms Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Atractylone exhibits diverse pharmacological effects, including anticancer and neuroprotection. A systematic review was conducted following PRISMA guidelines to analyze Atractylone. This study explores Atractylone's sources, biosynthesis, and therapeutic potential.
Hamza Elhrech, Oumayma Aguerd, Meriem El Fessikh, Zouhair Essahli, Taoufiq Benali, Waleed Al Abdulmonem, Learn‐Han Lee, Imane Chamkhi, Abdelhakim Bouyahya   +8 more
wiley   +1 more source

Geographic Differentiation of Essential Oil from Rhizome of Cultivated Atractylodes lancea by Using GC-MS and Chemical Pattern Recognition Analysis

Molecules, 2023
The rhizome of Atractylodes lancea (RAL) is a well-known Chinese herbal medicine (CHM) that has been applied in clinical settings for thousands of years.
Baohong Song, Wei Wang, Ruipeng Liu, Jinjin Cai, Yuanyuan Jiang, Xuemei Tang, Hongfei Wu, Hui Ao, Lu Chen   +8 more
doaj   +1 more source

Rhizosphere microbiome assemblage impacts soil chemical properties and medicinal quality in Atractylodes chinensis

Frontiers in Microbiology
IntroductionGeographic variation markedly influences Atractylodes chinensis medicinal quality, driven by rhizosphere processes regulating atractylodin accumulation.
Yang Lu, Xiaoyan Cao, Chunhan Qiao, Yingzhe Li, Jia Bai, Tian Zhang, Yu Cao, Chunying Zhao   +7 more
doaj   +1 more source