Results 151 to 160 of about 33,070 (201)

Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. [PDF]

Sci Adv, 2022
Yen YC, Schafer CT, Gustavsson M, Eberle SA, Dominik PK, Deneka D, Zhang P, Schall TJ, Kossiakoff AA, Tesmer JJG, Handel TM.   +10 more
europepmc   +1 more source

Atypical Chemokine Receptor 3 [PDF]

, 2020
openaire   +1 more source

An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

Nature Communications
Atherosclerosis is the underlying cause of myocardial infarction and ischemic stroke. It is a lipid-triggered and cytokine/chemokine-driven arterial inflammatory condition.
Omar El Bounkari, Chunfang Zan, Bishan Yang, Simon Ebert, Jonas Wagner, Elina Bugar, Naomi Kramer, Priscila Bourilhon, Christos Kontos, Marlies Zarwel, Dzmitry Sinitski, Jelena Milic, Yvonne Jansen, Wolfgang E. Kempf, Nadja Sachs, Lars Maegdefessel, Hao Ji, Ozgun Gokce, Fabien Riols, Mark Haid, Simona Gerra, Adrian Hoffmann, Markus Brandhofer, Maida Avdic, Richard Bucala, Remco T. A. Megens, Nienke Willemsen, Denise Messerer, Christian Schulz, Alexander Bartelt, Tobias Harm, Dominik Rath, Yvonne Döring, Meinrad Gawaz, Christian Weber, Aphrodite Kapurniotu, Jürgen Bernhagen   +36 more
doaj   +1 more source

The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia. [PDF]

Sci Adv, 2022
Karantanos T, Teodorescu P, Perkins B, Christodoulou I, Esteb C, Varadhan R, Helmenstine E, Rajkhowa T, Paun BC, Bonifant C, Dalton WB, Gondek LP, Moliterno AR, Levis MJ, Ghiaur G, Jones RJ.   +15 more
europepmc   +1 more source

Atypical Chemokine Receptor 1 [PDF]

, 2020
openaire   +1 more source

Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model. [PDF]

Cell Mol Life Sci, 2022
Van Loy T, De Jonghe S, Castermans K, Dheedene W, Stoop R, Verschuren L, Versele M, Chaltin P, Luttun A, Schols D.   +9 more
europepmc   +1 more source

Identification of critical residues at the C-terminal tip of ACKR4 regulating chemokine internalization and βarrestin involvement

Cell Communication and Signaling
Background Atypical chemokine receptors (ACKRs) play an important role in regulating the availability of chemokines and are responsible for the formation of chemokine gradients required for the directed migration of immune cells in health and disease ...
Oliver J. Gerken, Nicola Catone, Daniel F. Legler   +2 more
doaj   +1 more source

Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis. [PDF]

Acta Pharmacol Sin, 2022
Yang J, Miao RR, Li YN, Pan T, Wu SH, Qu XJ, Cui SX.   +6 more
europepmc   +1 more source

GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. [PDF]

Proc Natl Acad Sci U S A, 2021
Le Mercier A, Bonnavion R, Yu W, Alnouri MW, Ramas S, Zhang Y, Jäger Y, Roquid KA, Jeong HW, Sivaraj KK, Cho H, Chen X, Strilic B, Sijmonsma T, Adams R, Schroeder T, Rieger MA, Offermanns S.   +17 more
europepmc   +1 more source

Physiol Rep [PDF]

Inhalation of ozone (O|), a gaseous air pollutant, causes lung injury, lung inflammation, and airway hyperresponsiveness. Macrophages, mast cells, and neutrophils contribute to one or more of these sequelae induced by O|Furthermore, each of these ...

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