Results 111 to 120 of about 29,540 (247)

Clinical Significance of Uncommon, Non-Clinical, and Novel Autoantibodies

ImmunoTargets and Therapy
Michael R Shurin, Sarah E Wheeler Division of Clinical Immunopathology, Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USACorrespondence: Michael R Shurin, UPMC Immunopathology, 3477 Euler Way, CLB, Room 4024 ...
Shurin MR, Wheeler SE
doaj  

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Cathepsin S dominates autoantigen processing in human thymic dendritic cells

, 2012
The interaction of developing thymocytes with peptide-MHC complexes on thymic antigen presenting cells (APC) is crucial for T cell development, both for positive selection of "useful" thymocytes as well as negative selection of autoreactive thymocytes to
Reich, Michael, Kalbacher, Hubert, Thomas Rückrich, Tolosa, Eva, Michael Reich, Arthur Melms, Stoeckle, Christina, Hubert Kalbacher, Timo Burster, Eva Tolosa, Driessen, Christoph, Christoph Driessen, Stöckle, Christina, Paula Quecke, Melms, Arthur, Quecke, Paula, Burster, Timo, Weber, Ekkehard, Christina Stoeckle, Rückrich, Thomas, Ekkehard Weber   +20 more
core   +1 more source

Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case–Control Study

Oral Diseases, EarlyView.
ABSTRACT Objective To analyze the association between oral lichen planus (OLP), oral lichenoid lesions (OLL), and other comorbidities. Material and Methods A case–control study of 205 OLP, 96 OLL patients, and 301 age‐ and sex‐matched controls from Kuopio University Hospital was performed.
Mari Vehviläinen, Tuomas Selander, Tuula Salo, Maria Siponen   +3 more
wiley   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source

La autoantigen enhances translation of BiP mRNA

, 2001
Translational initiation of the human BiP mRNA is directed by an internal ribosomal entry site (IRES) located in the 5'-untranslated region (5'-UTR).
Back, SH, Lee, SH, Jang, SK, Rho, J, Kim, Yoon Ki   +4 more
core   +2 more sources

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Volume 78, Issue 7, Page 1490-1499, July 2026.
Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and posttranscriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron splicing ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Identification of a novel autoantigen eukaryotic initiation factor 3 associated with polymyositis

, 2019
Objectives: To describe the prevalence and clinical associations of autoantibodies to a novel autoantigen, eukaryotic initiation factor 3 (eIF3), detected in idiopathic inflammatory myositis.Methods: Sera or plasma from 678 polymyositis (PM) patients ...
Winer, John, Vencovsky, J., Betteridge, Zoë E., Chinoy, Hector; id_orcid, Cooper, R. G., Putchakayala, Kiran K., Danko, K., McHugh, NJ, Lundberg, I.   +8 more
core   +1 more source

autoantigen

Citation: 'autoantigen' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12914 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source