Results 21 to 30 of about 29,540 (247)

Oral delivery of bi-autoantigens by bacterium-like particles (BLPs) against autoimmune diabetes in NOD mice

Drug Delivery, 2023
Induction of oral tolerance by vaccination with type 1 diabetes mellitus (T1DM)-associated autoantigens exhibits great potential in preventing and treating this autoimmune disease.
Ruifeng Mao, Jin Wang, Ying Xu, Yuqi Wang, Mengmeng Wu, Lixia Mao, Yingying Chen, Dengchao Li, Tong Zhang, Enjie Diao, Zhenjing Chi, Yefu Wang, Xin Chang   +12 more
doaj   +1 more source

AAgAtlas 1.0: a human autoantigen database [PDF]

, 2016
: Autoantibodies refer to antibodies that target self-antigens, which can play pivotal roles in maintaining homeostasis, distinguishing normal from tumor tissue and trigger autoimmune diseases.

core   +1 more source

Cat# 7011, Isletest™ - islet cell autoantigen (IAA) ELISA

, 2021
Cat# 7011, Isletest™ - islet cell autoantigen (IAA ...
Yueshu Wang (11657593)
core   +1 more source

Enhanced Expression of Autoantigens During SARS-CoV-2 Viral Infection

Frontiers in Immunology, 2021
Immune homeostasis is disturbed during severe viral infections, which can lead to loss of tolerance to self-peptides and result in short- or long-term autoimmunity.
Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Samrein B. M. Ahmed, Samrein B. M. Ahmed, Suad Hannawi, Rifat Hamoudi, Rifat Hamoudi, Rifat Hamoudi, Qutayba Hamid, Qutayba Hamid, Qutayba Hamid, Rabih Halwani, Rabih Halwani, Rabih Halwani   +13 more
doaj   +1 more source

Case Report: Bullous Pemphigoid Associated With Morphea and Lichen Sclerosus: Coincidental Diseases or Pathogenetic Association?

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) represents the most common autoimmune bullous disease and is characterized by IgG autoantibodies targeting collagen XVII (BP180). BP has reportedly been occurred in association with other inflammatory skin diseases.
Roberto Maglie, Maria Efenesia Baffa, Francesca Montefusco, Carlo Pipitò, Stefano Senatore, Marco Capassoni, Marco Capassoni, Vincenza Maio, Marco Matucci Cerinic, Marco Matucci Cerinic, Emiliano Antiga, Serena Guiducci, Serena Guiducci   +12 more
doaj   +1 more source

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]

, 2008
Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate animal models, not much is known about their potential viral etiology. Infection
Hintereder, Gudrun, Gudrun Hintereder, Michael P. Manns, Christen, Urs, Herrath, Matthias G. von, Holdener, Martin, Monika Bayer, Johnson, Eric F., Urs Christen, Rodrigo, Evelyn, Frank J. Gonzalez, Pfeilschifter, Josef (Prof. Dr.), Eric F. Johnson, Evelyn Rodrigo, Gonzalez, Frank J., Martin Holdener, Edith Hintermann, Hintermann, Edith, Matthias von G. Herrath, Josef Pfeilschifter, Rhode, Antje, Bayer, Monika, Manns, Michael P., Antje Rhode   +23 more
core   +1 more source

Brain Antigens Stimulate Proliferation of T Lymphocytes With a Pathogenic Phenotype in Multiple Sclerosis Patients

Frontiers in Immunology, 2022
A method to stimulate T lymphocytes with a broad range of brain antigens would facilitate identification of the autoantigens for multiple sclerosis and enable definition of the pathogenic mechanisms important for multiple sclerosis.
Assaf Gottlieb, Hoai Phuong T. Pham, John William Lindsey   +2 more
doaj   +1 more source

Autoantigenicity of nucleolar complexes [PDF]

Autoimmunity Reviews, 2003
Autoantibodies targeting nucleolar autoantigens (ANoA) are most frequently found in sera from patients with systemic sclerosis (SSc, also designated scleroderma) or with SSc overlap syndromes. During the last decade an extensive number of nucleolar components have been identified and this allowed a more detailed analysis of the identity of nucleolar ...
Welting, T.J.M., Raijmakers, R., Pruijn, G.J.M.   +2 more
openaire   +2 more sources

B Quiet: Autoantigen-Specific Strategies to Silence Raucous B Lymphocytes and Halt Cross-Talk with T Cells in Type 1 Diabetes

Biomedicines, 2021
Islet autoantibodies are the primary biomarkers used to predict type 1 diabetes (T1D) disease risk. They signal immune tolerance breach by islet autoantigen-specific B lymphocytes.
Jamie L. Felton, Holly Conway, Rachel H. Bonami   +2 more
doaj   +1 more source

Identification of TRAPPC4 as a Key Autoantigen in Immune- Related Pancytopenia: Epitope Characterization and Immune Activation Mechanisms

Turkish Journal of Hematology
Objective: Immune-related pancytopenia (IRP) is characterized by autoantibody-mediated destruction or suppression of bone marrow cells, leading to pancytopenia.
Shanfeng Hao, Yang Zhang, Na Xiao, Zonghong Shao   +3 more
doaj   +1 more source