Results 91 to 100 of about 1,031,034 (270)

Unveiling the Interfacial Dynamics of Crosslinked Biodegradable Polycaprolactone Solid Polymer Electrolytes and Li Metal During Lithium Plating and Stripping via Operando ATR‐FTIR Spectroscopy

Advanced Science, EarlyView.
This study presents a comprehensive interfacial characterization of the biodegradable PCL solid‐polymer electrolytes (SPEs) with Li metal, utilizing an advanced operando ATR‐FTIR spectroscopy. The investigation elucidates the interphase properties during Li plating/stripping in a zero‐excess cell configuration.
Jian‐Fen Wang, Matthias Weiling, Felix Pfeiffer, Marian C. Stan, Martin Winter, Masoud Baghernejad   +5 more
wiley   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Priming and testing silicon patch-clamp neurochips

, 2014
We report on the systematic and automated priming and testing of silicon planar patch-clamp chips after their assembly in Plexiglas packages and sterilization in an air plasma reactor.
Zhao, Ping, Py, Christophe, Denhoff, Michael W., Shiu, Matthew, Sabourin, Nicaulas, Weber, John   +5 more
core   +1 more source

Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique. [PDF]

, 2014
Although ICRAC and other store-operated currents are often analyzed by Ca(2+) imaging, whole-cell patch clamp, described here, is the preferred technique to analyze ICRAC whenever possible.
Holzmann, Christian, Alansary, Dalia, Kilch, Tatiana, Peinelt, Christine, Hoth, Markus, Lis, Annette   +5 more
core   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

Advanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu, Xingyun Liu, Fangzhou Wang, Huili Ren, Chaojun Zhang, Ziyu Ren, Zunqi Liu, Jing Li   +7 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources

A novel methodology to characterize beat-to-beat alternations in whole-cell calcium currents.

PLoS ONE
An automated high-throughput procedure to quantify the degree of electrical beat-to-beat alternants in human atrial myocytes from electrophysiological recordings of the transmembrane ion currents of calcium ions (Ca2+) is presented and discussed.
Xavier Marimon, Miguel Cerrolaza, Carmen Tarifa, Leif Hove-Madsen   +3 more
doaj   +1 more source

Cost-Effective and Rapid Detection of Tetrodotoxin Using Indium Tin Oxide Electrodes via In Vitro Electrophysiology and Electrochemistry

Toxins
The real-time, cost-effective detection of marine toxins like tetrodotoxin (TTX) remains a significant challenge for the scientific community. Traditional methods, including cell-based assays (CBAs), high-performance liquid chromatography (HPLC), and ...
Naga Adithya Chandra Pandurangi, Manel M. Santafe, Angels Tudo, Nagihan Ozsoy, Fransesc X. Sureda, Mark L. Dallas, Ioanis Katakis   +6 more
doaj   +1 more source

Patch-clamp-Recordings

, 2018
Patch-clamp ...
Masayoshi Okada
core  

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source