Results 51 to 60 of about 5,861,967 (293)

Trajectory Prediction with Correction Mechanism for Connected and Autonomous Vehicles

, 2022
Trajectory prediction of surrounding vehicles is a critical task for connected and autonomous vehicles (CAVs), helping them to realize potential dangers in the traffic environment and make the most appropriate decisions.
Jia Xu, Hongbiao Liu, Pin Lv, Taoshen Li
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

External Force Field Modeling for Autonomous Surface Vehicles [PDF]

, 2020
In proceedings of International Symposium of Experimental Robotics (ISER ...
Jason Moulton, Nare Karapetyan, Alberto Quattrini Li, Ioannis M. Rekleitis   +3 more
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A-Star (A*) with Map Processing for the Global Path Planning of Autonomous Underwater and Surface Vehicles Operating in Large Areas

Applied Sciences
The global path planning system is one of the basic systems ensuring the autonomous operation of unmanned underwater vehicles (UUVs) and unmanned surface vehicles (USVs) in a complex aquatic environment.
Rafał Kot, Piotr Szymak, Paweł Piskur, Krzysztof Naus   +3 more
doaj   +1 more source

Collision-free Trajectory Planning for Autonomous Surface Vehicle [PDF]

2020 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM), 2020
In this paper, we propose an efficient and accurate method for autonomous surface vehicles to generate a smooth and collision-free trajectory considering its dynamics constraints. We decouple the trajectory planning problem as a front-end feasible path searching and a back-end kinodynamic trajectory optimization.
Licheng Wen, Jiaqing Yan, Xuemeng Yang, Yong Liu 0007, Yong Gu   +4 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oil Spill Mitigation with a Team of Heterogeneous Autonomous Vehicles

Journal of Marine Science and Engineering
This paper presents the implementation of an innovative solution based on heterogeneous autonomous vehicles to tackle maritime pollution (in particular, oil spills).
André Dias, Ana Mucha, Tiago Santos, Alexandre Oliveira, Guilherme Amaral, Hugo Ferreira, Alfredo Martins, José Almeida, Eduardo Silva   +8 more
doaj   +1 more source

Autonomous Surface Vehicle based docking for an Autonomous Underwater Vehicle

, 2017
Autonomous underwater vehicles have been used as tools for underwater operations. Autonomy means the capability to perform deliberative planning on-board without any human interaction. The levels of autonomy of underwater vehicles have been increasing over the years. One essential enabler for autonomous operation concerns docking.
openaire   +2 more sources