Results 21 to 30 of about 90,774 (312)
Dynamics of Autophagosome Formation [PDF]
Plant Physiology, 2017 Environmental stress activates autophagy and leads to autophagosome formation at the endoplasmic reticulum.
Junmarie Soto-Burgos +3 more
openaire +3 more sources
Autophagy and rheumatoid arthritis: Current knowledges and future perspectives [PDF]
, 2018 Autophagy is a degradation mechanism by which cells recycle cytoplasmic components to generate energy. By influencing lymphocyte development, survival, and proliferation, autophagy regulates the immune responses against self and non-self antigens ...
Alessandri, Cristiano +10 more
core +2 more sources
Molecular regulation of autophagosome formation [PDF]
Biochemical Society Transactions, 2022 Macroautophagy, hereafter autophagy, is a degradative process conserved among eukaryotes, which is essential to maintain cellular homeostasis. Defects in autophagy lead to numerous human diseases, including various types of cancer and neurodegenerative disorders.
Hu, Yan, Reggiori, Fulvio
openaire +2 more sources
Viruses, 2022 Our previous study has demonstrated that porcine pulmonary microvascular endothelial cells (MVECs) are susceptible to highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV).
Yanmei Wu +3 more
doaj +1 more source
Autophagy and the (pro)renin receptor
Frontiers in Endocrinology, 2013 The (pro)renin receptor (PRR) is a newly reported member of the renin-angiotensin system (RAS); a hormonal cascade responsible for regulating blood pressure.
Katrina Jean Binger, Dominik N Muller
doaj +1 more source
The lipid flippase Drs2 regulates anterograde transport of Atg9 during autophagy
Autophagy Reports, 2022 Macroautophagy/autophagy is a conserved catabolic pathway during which cellular material is sequestered within newly formed double-membrane vesicles called autophagosomes and delivered to the lytic compartment of eukaryotic cells for degradation ...
Franziska Kriegenburg +7 more
doaj +1 more source
Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H. +3 more
core +3 more sources
The Impact of Aging on Macroautophagy in the Pre-ovulatory Mouse Oocyte
Frontiers in Cell and Developmental Biology, 2021 Accompanying the precipitous age-related decline in human female fertility is an increase in the proportion of poor-quality oocytes within the ovary. The macroautophagy pathway, an essential protein degradation mechanism responsible for maintaining cell ...
Alexandra E. Peters +17 more
doaj +1 more source
DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose [PDF]
, 2015 Macroautophagy is a membrane-trafficking process that delivers cytoplasmic constituents to lysosomes for degradation. The process operates under basal conditions as a mechanism to turnover damaged or misfolded proteins and organelles. As a result, it has
A Kuma +47 more
core +2 more sources
Autophagy: A cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress [PDF]
, 2012 The role of autophagy in the response of human hepatocytes to oxidative stress remains unknown. Understanding this process may have important implications for the understanding of basic liver epithelial cell biology and the responses of hepatocytes ...
Biederbick A +7 more
core +1 more source