Results 71 to 80 of about 15,553 (191)
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.Background Carbapenem‐resistant Klebsiella pneumoniae (CRKP) has become a global public health threat, with significantly increased morbidity and mortality among high‐risk inpatients. High‐risk genotypes of CRKP, primarily including K. pneumoniae carbapenemase (KPC), oxacillinase‐48–like (OXA‐48–like), New Delhi metallo‐β‐lactamase (NDM), imipenemase ...
Qiongfang Zhang +5 more
wiley +1 more source
Empiric antibiotic therapy in urinary tract infection in patients with risk factors for antibiotic resistance in a German emergency department [PDF]
, 2018 Background: The aim of this study was to identify clinical risk factors for antimicrobial resistances and multidrug resistance (MDR) in urinary tract infections (UTI) in an emergency department in order to improve empirical therapy. Methods: UTI cases
Bischoff, Sebastian +4 more
core +1 more source
Distribution and Drug‐Resistance Analysis of Uropathogens in Urinary Tract Infections
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.Background Urinary tract infections (UTIs) are a major global health concern with increasing antimicrobial resistance. Regional data on pathogen distribution and resistance patterns are essential for guiding empirical therapy. This study aimed to investigate the distribution and antimicrobial resistance profiles of UTI pathogens in Shanghai, China, and
Weiyi Wu +4 more
wiley +1 more source
Case Reports in Critical Care, Volume 2026, Issue 1, 2026.Pancreatic encephalopathy (PE) is a rare but severe neurological complication of acute pancreatitis, characterized by cerebral edema and disruption of the blood–brain barrier due to systemic inflammation and the release of pancreatic enzymes. The pathophysiology involves a complex interplay of inflammatory cytokines and oxidative stress, leading to ...
Edith Joie Jewel M. Paras +3 more
wiley +1 more source
Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]
, 2017 Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R +3 more
core +2 more sources
Rapid emergence of resistance to broad-spectrum direct antimicrobial activity of avibactam
Microbiology SpectrumAvibactam (AVI) is a diazabicyclooctane (DBO) β-lactamase inhibitor used clinically in combination with ceftazidime. At concentrations higher than those typically achieved in vivo, it also has broad-spectrum direct antibacterial activity against ...
Michelle Nägeli +5 more
doaj +1 more source
A Rare Case of Prosthetic Joint Infection Caused by Group D Salmonella
Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.Prosthetic joint infections (PJIs) are gaining growing attention as a healthcare issue. Salmonella spp. is a rare cause of PJI, mostly involving hip arthroplasty rather than knee arthroplasty. Therefore, clinical experience on the management of PJI involving knee arthroplasties caused by Salmonella spp. is scant.
Anna Barbiero +8 more
wiley +1 more source
, 2017 Since 2010 the new antimicrobials introduced have activity against resistant Gram negative bacteria, long half-lives against Gram positive bacteria, better activity against Clostridium difficile, and safer antifungal properties. Limiting factors to using
Roland, Will
core +1 more source
Pharmacodynamics of meropenem and meropenem combined with avibactam against Klebsiella pneumoniae in an in vitro dynamic model [PDF]
Клиническая микробиология и антимикробная химиотерапияObjective. To study pharmacodynamics of meropenem alone and in combination with avibactam in an in vitro dynamic model; to evaluate effectiveness of meropenem against K.
Strukova E.N., golikova-mv.
doaj +1 more source
Interactions between Avibactam and Ceftazidime-Hydrolyzing Class D β-Lactamases
Biomolecules, 2020 Class D β-lactamases exhibit very heterogeneous hydrolysis activity spectra against the various types of clinically useful β-lactams. Similarly, and according to the available data, their sensitivities to inactivation by avibactam can vary by a
Jean-Marie Frère +6 more
doaj +1 more source