Results 81 to 90 of about 15,553 (191)
Background Myelodysplastic syndromes (MDSs) are clonal hematopoietic disorders often associated with cytogenetic abnormalities, among which trisomy 8 is one of the most common abnormalities. Trisomy 8 is linked to autoimmune manifestations, including Behçet‐like disease, especially with gastrointestinal involvement.
Zhan-Yue Niu +6 more
wiley +1 more source
Carbapenemase-producing organisms: a global scourge [PDF]
The dramatic increase in the prevalence and clinical impact of infections caused by bacteria producing carbapenemases is a global health concern.
Bonomo, Robert A +6 more
core
Risk factors and outcomes for ineffective empiric treatment of sepsis caused by gram-negative pathogens: Stratification by onset of infection [PDF]
Sepsis and septic shock remain serious consequences of infections, with reported mortality rates in excess of 40 percent. Timely antibiotic therapy in cases of sepsis and septic shock is recognized as an important determinant of outcome.
Hampton, Nicholas +2 more
core +2 more sources
This study evaluated clinically significant extended‐spectrum β‐lactamase (ESBL)‐ and AmpC β‐lactamase (AmpC)‐ producing Escherichia coli and Klebsiella pneumoniae in a cucumber production system, focusing on their potential sources and public health implications.
Manana Dlangalala +4 more
wiley +1 more source
Role of cephalosporins in the era of Clostridium difficile infection [PDF]
The incidence of Clostridium difficile infection (CDI) in Europe has increased markedly since 2000. Previous meta-analyses have suggested a strong association between cephalosporin use and CDI, and many national programmes on CDI control have focused on ...
Brogard +12 more
core +2 more sources
Klebsiella pneumoniae is associated with high antimicrobial resistance and is commonly isolated from colonization and healthcare‐associated infections (HAIs). This study is aimed at developing and validating molecular assays to detect resistance genes belonging to the bla family in resistant K. pneumoniae isolates.
Lavouisier F. B. Nogueira +14 more
wiley +1 more source
Management of KPC-Producing Klebsiella pneumoniae Infections [PDF]
Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) has become one of the most important contemporary pathogens, especially in endemic ...
M. Bassetti +142 more
core +2 more sources
Many antibiotics originate from soil‐inhabiting Actinobacteria, especially from the diverse genus Streptomyces. However, the emergence of antibiotic resistance poses a significant global challenge to treating infectious diseases. Therefore, the search for Actinobacteria, particularly from less‐explored environments, as potential sources of novel ...
Rajani Balkrishna Rao +6 more
wiley +1 more source
Effective antibiotic conservation by emergency antimicrobial stewardship during a drug shortage [PDF]
We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam
Casabar, Ed +8 more
core +2 more sources

