Flagellar Radial Spoke Protein 2 Is a Calmodulin Binding Protein Required for Motility in \u3cem\u3eChlamydomonas reinhardtii\u3c/em\u3e [PDF]
, 2004 Genetic and morphological studies have revealed that the radial spokes regulate ciliary and flagellar bending. Functional and biochemical analysis and the discovery of calmodulin in the radial spokes suggest that the regulatory mechanism involves control
Sale, Winfield S. +2 more
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Connecting two arrays: the emerging role of actin-microtubule cross-linking motor proteins [PDF]
, 2015 The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape, and morphogenesis ...
René Schneider, Staffan Persson
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The Coordination and Regulation of Axonemal Dynein [PDF]
Biophysical Journal, 2017 Molecular motor proteins drive the motility behind cellular dynamics. Recent advances in structural biology and single-molecule biophysics have led to a detailed understanding of many motor protein mechanisms. However, two understudied areas include the regulation and the coordination of motor proteins, particularly axonemal dyneins, which are the ...
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Physical Aspects of Axonemal Beating and Swimming
, 2000 We discuss a two-dimensional model for the dynamics of axonemal deformations driven by internally generated forces of molecular motors. Our model consists of an elastic filament pair connected by active elements.
Alberts B +27 more
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Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation [PDF]
, 2019 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Troetschel, C., Hamzeh, H., Alvarez, L., Pascal, R., Lavryk, F., Boenigk, W., Koerschen, H.
Alvarez, Luis +14 more
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The Flagellar Motility of \u3cem\u3eChlamydomonas pf25\u3c/em\u3e Mutant Lacking an AKAP-binding Protein Is Overtly Sensitive to Medium Conditions [PDF]
, 2006 Radial spokes are a conserved axonemal structural complex postulated to regulate the motility of 9 + 2 cilia and flagella via a network of phosphoenzymes and regulatory proteins.
Yang, Chun, Yang, Pinfen
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Analysis of the Movement of Chlamydomonas Flagella: The Function of the Radial-spoke System Is Revealed by Comparison of Wild-type and Mutant Flagella [PDF]
, 1982 The mutation uni-1 gives rise to uniflagellate Chlamydomonas cells which rotate around a fixed point in the microscope field, so that the flagellar bending pattern can be photographed easily .
Brokaw, C. J., Huang, B., Luck, D. J. L
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Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. [PDF]
, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Agard, David A +3 more
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Radial Spokes-A Snapshot of the Motility Regulation, Assembly, and Evolution of Cilia and Flagella [PDF]
, 2016 Propulsive forces generated by cilia and flagella are used in events that are critical for the thriving of diverse eukaryotic organisms in their environments. Despite distinctive strokes and regulations, the majority of them adopt the 9+2 axoneme that is
Liu, Yi, Yang, Pinfen, Zhu, Xiaoyan
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\u3cem\u3eChlamydomonas\u3c/em\u3e mutants display reversible deficiencies in flagellar beating and axonemal assembly [PDF]
, 2010 Axonemal complexes in flagella are largely prepackaged in the cell body. As such, one mutation often results in the absence of the co-assembled components and permanent motility deficiencies.
Mitchell, David R. +4 more
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