Results 81 to 90 of about 1,942 (177)
Shulin packages axonemal outer dynein arms for ciliary targeting
The main force generators in eukaryotic cilia and flagella are axonemal outer dynein arms (ODAs). During ciliogenesis, these ~1.8-megadalton complexes are assembled in the cytoplasm and targeted to cilia by an unknown mechanism. Here, we used the ciliate
Lau, Clinton K +9 more
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This study compares the role of electrostatics in the binding process between microtubules and two dynein microtubule-binding domains (MTBDs): cytoplasmic and axonemal.
Nayere Tajielyato, Emil Alexov
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In vitro gliding assays, in which microtubules are observed to glide over surfaces coated with motor proteins, are important tools for studying the biophysics of motility.
Howard, J., Tovar, M., Alper, J.
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Dynein is a large, complex microtubule mechanochemical translocator. Although discovered over 25 years ago in the axonemes of protozoa and sea urchin sperm flagella, relatively little is known about the structure and function of this important motor ...
Foltz, Kathleen Rae
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Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: Expression and predicted prohormone processing [PDF]
Proctolin was the first insect neuropeptide to be sequenced and has been the subject of many physiological and pharmacological studies in insects and crustaceans.
Isaac, R. E. +5 more
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Fine-tuning motile cilia and flagella: Evolution of the dynein motor proteins from plants to humans at high resolution. [PDF]
The flagellum is a key innovation linked to eukaryogenesis. It provides motility by regulated cycles of bending and bend propagation, which are thought to be controlled by a complex arrangement of seven distinct dyneins in repeated patterns of outer-(OAD)
Kollmar, M., Kollmar, Martin
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SummaryMicrotubule doublet (MTD) is the main skeleton of cilia/flagella. Many proteins, such as dyneins and radial spokes, bind to MTD, and generate or regulate force.
Shibata, Keitaro +5 more
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The IC138 and IC140 intermediate chains of the I1 axonemal dynein complex bind directly to tubulin
Dyneins are minus end directed microtubule motors that play a critical role in ciliary and flagellar movement. Ciliary dyneins, also known as axonemal dyneins, are characterized based on their location on the axoneme, either as outer dynein arms or inner
Rohrs, Henry W. +3 more
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A novel subunit of axonemal dynein conserved among lower and higher eukaryotes
To elucidate the subunit composition of axonemal inner-arm dynein, we examined a 38kDa protein (p38) co-purified with a Chlamydomonas inner arm subspecies, dynein d.
Yamamoto, Ryosuke +3 more
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Mechanochemical aspects of axonemal dynein activity studied by in vitro microtubule translocation
We have determined the relationship between microtubule length and translocation velocity from recordings of bovine brain microtubules translocating over a Paramecium 22S dynein substratum in an in vitro assay chamber.
Hamasaki, T. +3 more
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