Results 71 to 80 of about 1,942 (177)
Integrated control of axonemal dynein AAA+ motors [PDF]
Journal of Structural Biology, 2012 Axonemal dyneins are AAA(+) enzymes that convert ATP hydrolysis to mechanical work. This leads to the sliding of doublet microtubules with respect to each other and ultimately the generation of ciliary/flagellar beating. However, in order for useful work to be generated, the action of individual dynein motors must be precisely controlled.
openaire +2 more sources
Identification of the Outer-Inner Dynein Linker as a Hub Controller for Axonemal Dynein Activities [PDF]
Current Biology, 2013 In flagella, the outer dynein arm (ODA) and inner dynein arm (IDA) play distinct roles in generating beating motion. However, functional communications between the two dyneins have not been investigated.Here, we demonstrated by cryo-electron microscopy and chemical crosslinking that intermediate chain 2 (IC2) of ODAs interacts with the dynein ...
Oda, Toshiyuki +3 more
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Situs Inversus Totalis: A Case Report and Literature Review
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Situs Inversus Totalis (SIT) is a rare congenital anomaly characterized by the complete mirror‐image transposition of the thoracoabdominal viscera. Although typically it has a favorable prognosis, SIT can be associated with ciliopathy‐related disorders, most notably Primary Ciliary Dyskinesia (PCD).
Xin Du +4 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Kartagner syndrome is a rare congenital autosomal recessive disorder of ciliary movement, characterized by triad of chronic sinusitis, situs inversus and bronchiectasis leading to recurrent chest and sinuses infections. The primary objectives of this case report is to highlight the presentation of this rare disorder, its surgical challenge ...
Pakeezah Tabasum +5 more
wiley +1 more source
, 2017 Left-right-differentiation is conserved in all vertebrates, also is the orientation of internal organs defined to either the left or the right side and the viscera are rotated in a certain direction.
Schröder, Silke Sabina
core +1 more source
The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice
Andrology, Volume 14, Issue 2, Page 545-554, February 2026.Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma +7 more
wiley +1 more source
International Journal of Cancer, Volume 158, Issue 1, Page 120-130, 1 January 2026.What's new? Colorectal cancer (CRC) frequently metastasizes to the liver, either synchronously with primary diagnosis or metachronously, after variable time intervals. Although implicated, the role of genetic factors in driving synchronous and metachronous disease progression remains uncertain.
Marie Rajtmajerova +16 more
wiley +1 more source
, 2004 Members of the LC7/Roadblock family of light chains (LCs) have been found in both cytoplasmic and axonemal dyneins. LC7a was originally identified within Chlamydomonas outer arm dynein and associates with this motor’s cargo-binding region.
Gregory J. Pazour +4 more
core +1 more source
Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.ABSTRACT Purpose Mammalian sperm require a large amount of ATP to sustain motility. While glycolysis and oxidative phosphorylation (OXPHOS) are established ATP sources, they cannot fully explain motility maintenance under glucose‐deprived conditions.
Kosei Oishi +9 more
wiley +1 more source
, 2014 CG31320/HEATR2 orthologues are found in species with cilia/flagella that have motile function and retain elements of the axonemal dyneins required for this motility. Species which have no cilia (ie.
Ian M. Carr (141801) +23 more
core +1 more source