Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease [PDF]
, 2017 The Niemann-Pick type C1 (NPC1) disease is a neurodegenerative lysosomal storage disorder due to mutations in the NPC1 gene, encoding a transmembrane protein related to the Sonic hedgehog receptor, Patched, and involved in intracellular trafficking of ...
Canterini, Sonia +7 more
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Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission
Life Science Alliance, 2019 This comprehensive study describes the key role and real-time dynamics of Plasmodium kinesin-8B in microtubule-based basal body and axoneme assembly during flagellum (male gamete) formation and parasite transmission.
Mohammad Zeeshan +12 more
doaj +1 more source
Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. [PDF]
, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Agard, David A +3 more
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The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction. [PDF]
, 2016 Male Seminal Fluid Proteins (SFPs) transferred during copulation modulate female reproductive physiology and behavior, impacting sperm storage/use, ovulation, oviposition, and remating receptivity.
Abd-Alla, Adly MM +8 more
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Phosphoproteins associated with cyclic nucleotide stimulation of ciliary motility in Paramecium [PDF]
, 1990 Permeabilized, MgATP-reactivated cells of Paramecium (models) respond to cyclic AMP and cyclic GMP by increasing forward swimming speed. In association with the motile response, cyclic AMP and 8-bromo-cyclic GMP (8-Br-cyclic GMP) stimulated protein ...
Bonini, Nancy M., Nelson, David L.
core
Cfap97d1 is important for flagellar axoneme maintenance and male mouse fertility.
PLoS Genetics, 2020 The flagellum is essential for sperm motility and fertilization in vivo. The axoneme is the main component of the flagella, extending through its entire length.
Seiya Oura +11 more
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CellsMouse sperm-associated antigen 6-like (SPAG6L) evolved from SPAG6, the mammalian ortholog of Chlamydomonas PF16, which is localized in the central apparatus of the motile cilia and is essential for ciliary motility.
Tao Li +6 more
doaj +1 more source
Cilia Distal Domain: Diversity in Evolutionarily Conserved Structures
Cells, 2019 Eukaryotic cilia are microtubule-based organelles that protrude from the cell surface to fulfill sensory and motility functions. Their basic structure consists of an axoneme templated by a centriole/basal body.
Helena Soares +4 more
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The Flagellar Motility of \u3cem\u3eChlamydomonas pf25\u3c/em\u3e Mutant Lacking an AKAP-binding Protein Is Overtly Sensitive to Medium Conditions [PDF]
, 2006 Radial spokes are a conserved axonemal structural complex postulated to regulate the motility of 9 + 2 cilia and flagella via a network of phosphoenzymes and regulatory proteins.
Yang, Chun, Yang, Pinfen
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Generic aspects of axonemal beating
New Journal of Physics, 2000 We study the dynamics of an elastic rod-like filament in two dimensions, driven by internally generated forces. This situation is motivated by cilia and flagella which contain an axoneme. These hair-like appendages of many cells are used for swimming and to stir surrounding fluids.
Sébastien Camalet, Frank Jülicher
openaire +1 more source