Sperm-associated antigen 6 (SPAG6) deficiency and defects in ciliogenesis and cilia function: polarity, density, and beat. [PDF]
SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6-deficient mice die with hydrocephalus, and surviving males are sterile because of sperm motility defects.
Maria E Teves +10 more
doaj +1 more source
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry [PDF]
Ciliopathies are a group of genetically heterogeneous disorders, characterized by defects in cilia genesis or maintenance. Mutations in the RPGR gene and its interacting partners, RPGRIP1 and RPGRIP1L, cause ciliopathies, but the function of their ...
Aguirre +68 more
core +3 more sources
Abstract Colored snow caused by green algae (Chlorophyceae) is well known, but melting snowpacks can also harbor golden‐brown blooms consisting of Chrysophyceae. We collected 14 samples of cryoflora in the Austrian and Swiss Alps, the High Tatras in Slovakia, and in Arctic Svalbard. Eight laboratory unicellular flagellated strains were established from
Lenka Procházková +6 more
wiley +1 more source
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function
The dynein-2 microtubule motor is the retrograde motor for intraflagellar transport. Mutations in dynein-2 components cause skeletal ciliopathies, notably Jeune syndrome. Dynein-2 contains a heterodimer of two non-identical intermediate chains, WDR34 and
Laura Vuolo +3 more
doaj +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Resolving Trypanosoma brucei Flagellar Structure by Cryo-Electron Tomography [PDF]
Trypanosoma brucei is a unicellular eukaryote that can cause human African trypanosomiasis, which has continued to evolve and spread. The key feature of these parasites is that they have a flagellum consists of a typical 9 + 2 axoneme and a lattice-like ...
Dai Jennifer
doaj +1 more source
Analysis of the Movement of Chlamydomonas Flagella: The Function of the Radial-spoke System Is Revealed by Comparison of Wild-type and Mutant Flagella [PDF]
The mutation uni-1 gives rise to uniflagellate Chlamydomonas cells which rotate around a fixed point in the microscope field, so that the flagellar bending pattern can be photographed easily .
Brokaw, C. J., Huang, B., Luck, D. J. L
core
ABSTRACT Barthelona is a genus of anaerobic flagellates that forms a sister lineage to Fornicata along with Skoliomonas. Although “Barthelona spp.” are known to separate into three distinct lineages, their detailed morphology has not been examined, and their taxonomic classification is incomplete.
Takashi Shiratori +4 more
wiley +1 more source
Radial Spokes-A Snapshot of the Motility Regulation, Assembly, and Evolution of Cilia and Flagella [PDF]
Propulsive forces generated by cilia and flagella are used in events that are critical for the thriving of diverse eukaryotic organisms in their environments. Despite distinctive strokes and regulations, the majority of them adopt the 9+2 axoneme that is
Liu, Yi, Yang, Pinfen, Zhu, Xiaoyan
core +1 more source
The C. elegans tubulin family is composed of nine α-, six β-, and one γ-tubulin. Tubulins are highly conserved, functioning as α-β heterodimers that assemble into microtubules.
Hurd, Daryl D.
core +2 more sources

