Results 71 to 80 of about 12,013 (227)

The biomechanical role of extra-axonemal structures in shaping the flagellar beat of Euglena gracilis

eLife, 2021
We propose and discuss a model for flagellar mechanics in Euglena gracilis. We show that the peculiar non-planar shapes of its beating flagellum, dubbed 'spinning lasso', arise from the mechanical interactions between two of its inner components, namely,
Giancarlo Cicconofri, Giovanni Noselli, Antonio DeSimone   +2 more
doaj   +1 more source

Axonemal radial spokes [PDF]

BioArchitecture, 2012
The radial spoke (RS) is a complex of at least 23 proteins that works as a mechanochemical transducer between the central-pair apparatus and the peripheral microtubule doublets in eukaryotic flagella and motile cilia. The RS contributes to the regulation of the activity of dynein motors, and thus to flagellar motility.
Gaia, Pigino, Takashi, Ishikawa
openaire   +2 more sources

New Insights Into the Three‐Dimensional Mechanics of the Flagellar Beat Cycle

Cytoskeleton, EarlyView.
ABSTRACT Advances in imaging at the molecular scale have provided greater detail concerning the three‐dimensional structure of the ciliary/flagellar axoneme. Additionally, it has recently been confirmed that electrostatic forces regulate the dynein‐tubulin interaction at the microtubule binding domain (MTBD) of dynein, and at the junction of the nexin ...
Charles B. Lindemann
wiley   +1 more source

mbo2 Axoneme 4

, 2016
Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank, Howard, Jonathon, Veikko F. Geyer (3326802), Jonathon Howard (187861), Sartori, Pablo, Geyer, Veikko F., Frank Jülicher (77675), Andre Scholich (3326805), Scholich, Andre, Pablo Sartori (673523)   +9 more
core   +1 more source

Chlamydomonas as a model system to study cilia and flagella using genetics, biochemistry, and microscopy

Frontiers in Cell and Developmental Biology
The unicellular green alga, Chlamydomonas reinhardtii, has played a central role in discovering much of what is currently known about the composition, assembly, and function of cilia and flagella.
Wallace F. Marshall
doaj   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

mbo2 Axoneme 6

, 2016
Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank, Howard, Jonathon, Veikko F. Geyer (3326802), Jonathon Howard (187861), Sartori, Pablo, Geyer, Veikko F., Frank Jülicher (77675), Andre Scholich (3326805), Scholich, Andre, Pablo Sartori (673523)   +9 more
core   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

mbo2 Axoneme 5

, 2016
Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank, Howard, Jonathon, Veikko F. Geyer (3326802), Jonathon Howard (187861), Sartori, Pablo, Geyer, Veikko F., Frank Jülicher (77675), Andre Scholich (3326805), Scholich, Andre, Pablo Sartori (673523)   +9 more
core   +1 more source

Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species

Andrology, EarlyView.
ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak, Brian J. Galletta, Nasser M. Rusan   +2 more
wiley   +1 more source