Results 61 to 70 of about 12,013 (227)
Probing Dynein Motor Activity in the Intact Chlamydomonas Axoneme [PDF]
, 2019 Eukaryotic flagella and cilia are long rod-like extensions of cells, which play a fundamental role in single cell movement, as well as in fluid transport. Flagella and cilia contain a highly evolutionary conserved mechanical structure called the axoneme.
Feofilova, Maria
core +3 more sources
Cytoskeleton, EarlyView.ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source
eLife, 2020 Microtubules are cytoskeletal structures involved in stability, transport and organization in the cell. The building blocks, the α- and β-tubulin heterodimers, form protofilaments that associate laterally into the hollow microtubule.
Ahmad Abdelzaher Zaki Khalifa +12 more
doaj +1 more source
, 2016 Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank +9 more
core +1 more source
Molecular basis of the morphogenesis of sperm head and tail in mice
Reproductive Medicine and Biology, 2022 Background The spermatozoon has a complex molecular apparatus necessary for fertilization in its head and flagellum. Recently, numerous genes that are needed to construct the molecular apparatus of spermatozoa have been identified through the analysis of
Keiichiro Yogo
doaj +1 more source
Cytoplasmic factories for axonemal dynein assembly [PDF]
Journal of Cell Science, 2021 ABSTRACT Axonemal dyneins power the beating of motile cilia and flagella. These massive multimeric motor complexes are assembled in the cytoplasm, and subsequently trafficked to cilia and incorporated into the axonemal superstructure. Numerous cytoplasmic factors are required for the dynein assembly process, and, in mammals, defects lead
openaire +2 more sources
Cytoskeleton, EarlyView.ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen +2 more
wiley +1 more source
, 2016 Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank +9 more
core +1 more source
Axoneme-specific β-tubulin specialization a conserved C-terminal motif specifies the central pair [PDF]
, 2001 Axonemes are ancient organelles that mediate motility of cilia and flagella in animals, plants, and protists. The long evolutionary conservation of axoneme architecture, a cylinder of nine doublet microtubules surrounding a central pair of singlet ...
Turner, F.Rudolf +7 more
core +1 more source
Microtubule-Associated Proteins: From Dynamic Regulation of Microtubules to Cellular Architecture
CellsMicrotubule-associated proteins (MAPs) are key regulators of microtubule architecture and dynamics, orchestrating microtubule stability, post-translational modification, and spatial organization across diverse cellular contexts. Through these activities,
Eva Pais, Kenneth Bødtker Schou
doaj +1 more source