Results 51 to 60 of about 12,013 (227)
, 2016 Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank +9 more
core +1 more source
Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei
eLife, 2014 Defects in flagella growth are related to a number of human diseases. Central to flagellar growth is the organization of microtubules that polymerize from basal bodies to form the axoneme, which consists of hundreds of proteins.
Johanna L Höög +5 more
doaj +1 more source
Second harmonic microscopy of axonemes
Optics Express, 2009 We performed Second Harmonic Microscopy of axonemes obtained from sea urchin sperm. Using polarization analysis and a trade-off between signal and photodamage, we were able to determine, for the first time to our knowledge, the nonlinear susceptibility chizxx/chixzx = 1.1+/-0.2 and chizzz/chixzx = 4+/-0.5 of axonemes.
Odin, Christophe +3 more
openaire +3 more sources
Advanced Science, EarlyView.Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
, 2016 Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank +9 more
core +1 more source
Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, EarlyView.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
, 2016 Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Veikko F. Geyer (3326802) +4 more
core +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
, 2016 Movie and waveform of a reactivated axoneme, isolated from a Chlamydomonas reinhardtii mbo2 mutant cell (CC-2377 mbo2 mt-
Jülicher, Frank +9 more
core +1 more source
Radial spoke protein 9 is necessary for axoneme assembly in Plasmodium but not in trypanosomatid parasites [PDF]
, 2023 Flagella are important for eukaryote cell motility, including in sperm, and are vital for life cycle progression of many unicellular eukaryotic pathogens. The ‘9+2’ axoneme in most motile flagella comprises nine outer doublet and two central-pair singlet
Kohl, Linda +10 more
core +1 more source