Results 41 to 50 of about 8,323 (256)

Solvent-controlled selective transformation of 2-Bromomethyl-2-methylaziridines to functionalized Aziridines and Azetidines [PDF]

, 2012
The reactivity of 2-bromomethyl-2-methylaziridines toward oxygen, sulfur, and carbon nucleophiles in different solvent systems was investigated. Remarkably, the choice of the solvent has a profound influence on the reaction outcome, enabling the ...
Catak, Saron, D'hooghe, Matthias, De Kimpe, Norbert, Goossens, Hannelore, Stanković, Sonja, Tezcan, Meniz, Van Speybroeck, Veronique, Waroquier, Michel   +7 more
core   +1 more source

4-Membered Ring Carbocations: A Positive Development in the Synthesis of 3,3-Disubstituted Oxetanes and Azetidines

CHIMIA, 2023
4-Membered heterocycles are low molecular weight polar scaffolds with intriguing potential for drug discovery. Despite their unquestionable value, methods to access such heterocycles remain scant.
Juan J. Rojas, James A. Bull
doaj   +1 more source

Synthesis of New Azetidine and Oxetane Amino Acid Derivatives through Aza-Michael Addition of NH-Heterocycles with Methyl 2-(Azetidin- or Oxetan-3-Ylidene)Acetates

Molecules, 2023
In this paper, a simple and efficient synthetic route for the preparation of new heterocyclic amino acid derivatives containing azetidine and oxetane rings was described.
Emilis Gudelis, Sonata Krikštolaitytė, Monika Stančiauskaitė, Urtė Šachlevičiūtė, Aurimas Bieliauskas, Vaida Milišiūnaitė, Rokas Jankauskas, Neringa Kleizienė, Frank A. Sløk, Algirdas Šačkus   +9 more
doaj   +1 more source

Inter-and Intramolecular (4+3) Cycloadditions With Epoxy Allylsilanes as Dienophiles. [PDF]

Chem Asian J
Methylenated cycloheptanoids are synthesized by formal (4+3) cycloadditions of dienes with epoxy allylsilanes as dienophiles in the presence of catalytic amounts of TESOTf. Intermolecular and intramolecular (4+3) cycloadditions with dienes including furans, cyclopentadiene, pyrroles, thiophenes, and benzenes proceeded to provide polycyclic adducts in ...
Teo QH, Zhou Y, Krenske EH, Chiu P.
europepmc   +2 more sources

Reaction of Azetidines with Chloroformates. [PDF]

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Couty, François, Evano, Gwilherm, Vargas-Sanchez, Monica, Lakhdar, Sami   +3 more
openaire   +2 more sources

Organocatalytic Access to Enantioenriched Spirooxindole-Based 4-Methyleneazetidines

Molecules, 2017
This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates ...
Giulia Rainoldi, Matteo Faltracco, Claudia Spatti, Alessandra Silvani, Giordano Lesma   +4 more
doaj   +1 more source

Passerini Reactions on Biocatalytically Derived Chiral Azetidines

Molecules, 2016
The purpose of this study was to explore a series of Passerini reactions on a biocatalytically derived enantiopure azetidine-2-carboxyaldehyde in order to obtain, in a diastereoselective manner, polyfunctionalised derivatives having the potential to be ...
Lisa Moni, Luca Banfi, Andrea Basso, Andrea Bozzano, Martina Spallarossa, Ludger Wessjohann, Renata Riva   +6 more
doaj   +1 more source

An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]

, 2018
Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
core   +1 more source

Synthesis of azetidines via visible-light-mediated intermolecular [2+2] photocycloadditions

Nature Chemistry, 2020
Intermolecular [2+2] photocycloadditions represent a powerful method for the synthesis of highly strained, four-membered rings. Although this approach is commonly employed for the synthesis of oxetanes and cyclobutanes, the synthesis of azetidines via ...
M. Becker, E. Wearing, C. Schindler
semanticscholar   +1 more source

Azetidinylideneketenimines as a Multimodal Synthetic Platform: Coordination Chemistry and Cycloaddition‐Triggered Transformations

Angewandte Chemie, EarlyView.
Cross‐coupling/homologation sequence between a stable three‐membered‐ring carbene and isocyanides enables facile and rapid access to novel methyleneketenimines and the first bis(methyleneketenimine). Reactivity studies gave rise to the first methyleneketenimine‐transition metal complexes, unique multimodal reactivity ranging from CO2, isocyanate ...
Taichi Koike, Keisuke Ito, Shintaro Ishida, Takeaki Iwamoto   +3 more
wiley   +2 more sources