Results 21 to 30 of about 2,054 (167)

TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines

Molecules, 2013
We report herein an original and rapid synthesis of 2,3-diaryl N-tosylaziridines by TDAE strategy starting from ortho- or para-nitro(dichloromethyl)benzene derivatives and N-tosylimines. A mixture of cis/trans isomers was isolated from 1-(dichloromethyl)-
Thierry Terme, Cédric Spitz, Omar Khoumeri, Patrice Vanelle   +3 more
doaj   +1 more source

Bach Goes to Town

Biomolecules, 2018
Donald A. Tomalia is one of the pioneers in the field of dendrimers, who is still active at the age of 80 years-old. The present contribution is a journey through his scientific contributions from the early beginning until his discovery of the poly ...
Jørn Bolstad Christensen
doaj   +1 more source

Strained Ammonium Precursors for Radiofluorinations

ChemistryOpen, 2022
The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of novel and versatile techniques to introduce fluorine‐18, especially for the radiolabelling of biologically or ...
Dr. Falco Reissig, Dr. Constantin Mamat
doaj   +1 more source

Stereoselective Multicomponent Reactions in the Synthesis or Transformations of Epoxides and Aziridines

Molecules, 2019
Small ring heterocycles, such as epoxides and aziridines, are present in several natural products and are also highly versatile building blocks, frequently involved in the synthesis of numerous bioactive products and pharmaceuticals.
Allan Ribeiro da Silva, Deborah Araujo dos Santos, Marcio Weber Paixão, Arlene Gonçalves Corrêa   +3 more
doaj   +1 more source

Allylic alcohols and amines by carbenoid eliminative cross-coupling using epoxides or aziridines

Beilstein Journal of Organic Chemistry, 2021
α-Lithiated terminal epoxides and N-(tert-butylsulfonyl)aziridines undergo eliminative cross-coupling with α-lithio ethers, to give convergent access to allylic alcohols and allylic amines, respectively.
Matthew J. Fleming, David M. Hodgson
doaj   +1 more source

Chemical Upcycling of Nitrile Butadiene Rubbers to Polyamines and Polyols by Chemoselective Catalytic Hydrogenation

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
We demonstrate here the transformation of NBR (Nitrile butadiene rubber) including post‐consumer waste sourced from nitrile gloves and o‐rings into polyamines and polyols via ruthenium catalyzed hydrogenation. ABSTRACT We report here two new approaches for the chemical recycling/upcycling of nitrile butadiene rubber (NBR) to make either polyamines or ...
Alejandra Sophia Lozano Perez, Raymundo Marcial‐Hernandez, Harini Sampathkumar, Oluchi Emenike, Ketan Pancholi, Claire N. Brodie, Daniel M. Dawson, Amit Kumar   +7 more
wiley   +2 more sources

Transition metal-free Csp3-Csp3 bond-forming reactions of N-tosylaziridines and gem-diborylalkanes

Green Synthesis and Catalysis
The incorporation of additional Csp3 atoms into candidate drugs may enhance their pharmacological properties. Nevertheless, it remains challenging to construct desired Csp3-Csp3 bonds efficiently and practically.
Pu-Zhang Zi, Quan-Hong Zhao, Zhan-Cai Ma, Xiao-Lin Ren, Xing-Bang Liu, Yi-Wei Qiao, Lin-Wen Wei, Song Liu, Yuan Huang   +8 more
doaj   +1 more source

Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents

Molecules, 2014
By using the Suzuki-Miyaura protocol, a simple straightforward synthesis of functionalized 2-arylaziridines has been developed. By means of this synthetic strategy from readily available ortho-, meta- and para-bromophenylaziridines and aryl- or ...
Arianna Giovine, Marilena Muraglia, Marco Antonio Florio, Antonio Rosato, Filomena Corbo, Carlo Franchini, Biagia Musio, Leonardo Degennaro, Renzo Luisi   +8 more
doaj   +1 more source

Modular Rh‐Catalyzed Synthesis and Biological Profiling of Diverse Pentafluorobenzenesulfonamide Reactive Fragments

Chemistry – A European Journal, EarlyView.
A modular Rh‐catalyzed synthetic approach enabled the preparation of diverse reactive fragments from available substrates. The reactive fragments modified Aurora A kinase via several distinct modification reaction classes. In a complex biological environment, the constellation of modified proteins depended critically on the reactive fragment structure.
Julian Chesti, Jennifer A. Miles, George J. Wade, Scott Grossman, George W. Preston, Richard Bayliss, Stuart L. Warriner, Megan H. Wright, Adam Nelson   +8 more
wiley   +1 more source

Enantioselective synthesis of aziridines using asymmetric transfer hydrogenation as a precursor for chiral derivatives used as bonding agent for rocket solid propellants

Química Nova, 2002
A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of a-amino ketones and cyclisation through treatment with tosyl chloride and ...
Aparecida M. Kawamoto, Martin Wills
doaj   +1 more source