Results 31 to 40 of about 6,575 (208)

Strained Ammonium Precursors for Radiofluorinations

ChemistryOpen, 2022
The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of novel and versatile techniques to introduce fluorine‐18, especially for the radiolabelling of biologically or ...
Dr. Falco Reissig, Dr. Constantin Mamat
doaj   +1 more source

Stereoselective Multicomponent Reactions in the Synthesis or Transformations of Epoxides and Aziridines

Molecules, 2019
Small ring heterocycles, such as epoxides and aziridines, are present in several natural products and are also highly versatile building blocks, frequently involved in the synthesis of numerous bioactive products and pharmaceuticals.
Allan Ribeiro da Silva, Deborah Araujo dos Santos, Marcio Weber Paixão, Arlene Gonçalves Corrêa   +3 more
doaj   +1 more source

Silver-Catalyzed Trifluoromethoxylation of Aziridines

, 2022
We disclose a silver-catalyzed trifluoromethoxylation of N-tosyl aziridines with trifluoromethyl arylsulfonate. The protocol is characterized by its mild conditions, simple operations, and good chemo- and regioselectivity.
Xiangyu Deng (5181719), Jingrui Xin (11943465), Pingping Tang, Xiangyu Deng, Jingrui Xin, Pingping Tang (1470787)   +5 more
core   +1 more source

Allylic alcohols and amines by carbenoid eliminative cross-coupling using epoxides or aziridines

Beilstein Journal of Organic Chemistry, 2021
α-Lithiated terminal epoxides and N-(tert-butylsulfonyl)aziridines undergo eliminative cross-coupling with α-lithio ethers, to give convergent access to allylic alcohols and allylic amines, respectively.
Matthew J. Fleming, David M. Hodgson
doaj   +1 more source

Transition metal-free Csp3-Csp3 bond-forming reactions of N-tosylaziridines and gem-diborylalkanes

Green Synthesis and Catalysis
The incorporation of additional Csp3 atoms into candidate drugs may enhance their pharmacological properties. Nevertheless, it remains challenging to construct desired Csp3-Csp3 bonds efficiently and practically.
Pu-Zhang Zi, Quan-Hong Zhao, Zhan-Cai Ma, Xiao-Lin Ren, Xing-Bang Liu, Yi-Wei Qiao, Lin-Wen Wei, Song Liu, Yuan Huang   +8 more
doaj   +1 more source

Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents

Molecules, 2014
By using the Suzuki-Miyaura protocol, a simple straightforward synthesis of functionalized 2-arylaziridines has been developed. By means of this synthetic strategy from readily available ortho-, meta- and para-bromophenylaziridines and aryl- or ...
Arianna Giovine, Marilena Muraglia, Marco Antonio Florio, Antonio Rosato, Filomena Corbo, Carlo Franchini, Biagia Musio, Leonardo Degennaro, Renzo Luisi   +8 more
doaj   +1 more source

Enantioselective synthesis of aziridines using asymmetric transfer hydrogenation as a precursor for chiral derivatives used as bonding agent for rocket solid propellants

Química Nova, 2002
A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of a-amino ketones and cyclisation through treatment with tosyl chloride and ...
Aparecida M. Kawamoto, Martin Wills
doaj   +1 more source

‐Sulfonyl Aziridines and Cyclic Anhydrides

, 2020
We report a new synthetic methodology for poly(ester amide)s by anionic ring-opening copolymerization of N -sulfonyl aziridines and cyclic anhydrides.
Nikos Hadjichristidis, Hadjichristidis, Nikos, Xu, Jiaxi, Jiaxi Xu   +3 more
core   +1 more source

Recent Advances in Transition Metal-Catalyzed Ring-Opening Reaction of Aziridine

Compounds
The smallest strained, saturated N-heterocycles, such as aziridine, can be a valuable building block in synthetic organic chemistry. Ring-opening reactions with various nucleophiles could be the most important strategy to synthesize various value-added ...
Partha Sarathi Bera, Yafia Kousin Mirza, Tarunika Sachdeva, Milan Bera   +3 more
doaj   +1 more source

Efficient synthesis of ethyl 2-(oxazolin-2-yl)alkanoates via ethoxycarbonylketene-induced electrophilic ring expansion of aziridines

Beilstein Journal of Organic Chemistry, 2022
Alkyl 2-diazo-3-oxoalkanoates generate alkoxycarbonylketenes, which undergo an electrophilic ring expansion with aziridines to afford alkyl 2-(oxazolin-2-yl)alkanoates in good to excellent yields under microwave heating.
Yelong Lei, Jiaxi Xu
doaj   +1 more source