Results 41 to 50 of about 6,575 (208)

Rhodium(III)-Catalyzed C-C Coupling between Arenes and Aziridines by C-H Activation

, 2013
Rhodium(III)-Catalyzed C-C Coupling between Arenes and Aziridines by C-H ...
Wan, Boshun, 李兴伟, Yu, Xinzhang, Yu, Songjie, Wang, Fen, Li, Xingwei, 万伯顺   +6 more
core   +1 more source

The synthesis and reactivity of N-diphenylphosphinyl aziridines

, 1994
The synthesis of enantiopure N-diphenylphosphinyl (Dpp) protected aziridines from 2-aminoalcohols and the reactions of these aziridines with a range of nucleophiles is ...
Howson, Bill, Sweeney, J. B., Osborn, Helen M.I.   +2 more
core   +5 more sources

Synthesis of 2-amino-3-arylpropan-1-ols and 1-(2,3-diaminopropyl)-1,2,3-triazoles and evaluation of their antimalarial activity

Beilstein Journal of Organic Chemistry, 2011
A variety of 2-amino-3-arylpropan-1-ols, anti-2-amino-3-aryl-3-methoxypropan-1-ols and anti-2-amino-1-arylpropan-1,3-diols were prepared selectively through elaboration of trans-4-aryl-3-chloro-β-lactams.
Matthias D’hooghe, Stéphanie Vandekerckhove, Karen Mollet, Karel Vervisch, Stijn Dekeukeleire, Liesbeth Lehoucq, Carmen Lategan, Peter J. Smith, Kelly Chibale, Norbert De Kimpe   +9 more
doaj   +1 more source

Deprotection of Sulfonyl Aziridines

, 2016
The deprotection of the chiral N-sulfonyl aziridines 1−3 has been studied under different desulfonylation conditions. Two methods for the efficient deprotection of 2-benzyl-, 2-phenyl-, and 2-carboxyl-N-sulfonylaziridines were found.
Diego A. Alonso (2145664), Pher G. Andersson (1478632)   +1 more
core   +1 more source

Synthesis of α-Aminophosphonic Acid Derivatives Through the Addition of O- and S-Nucleophiles to 2H-Azirines and Their Antiproliferative Effect on A549 Human Lung Adenocarcinoma Cells

Molecules, 2020
This work reports a straightforward regioselective synthetic methodology to prepare α-aminophosphine oxides and phosphonates through the addition of oxygen and sulfur nucleophiles to the C–N double bond of 2H-azirine derivatives. Determined by the nature
Victor Carramiñana, Ana M. Ochoa de Retana, Francisco Palacios, Jesús M. de los Santos   +3 more
doaj   +1 more source

Intermolecular 3+3 Ring Expansion of Aziridines to Dehydropiperidines through the Intermediacy of Aziridinium Ylides [PDF]

, 2019
Bicyclic aziridines undergo formal [3+3] ring expansion reactions when exposed to rhodium-bound vinyl carbenes to form complex dehydropiperidines in a highly stereocontrolled rearrangement.
Jennifer, Schomaker, Kate A., Nicastri, Ilia A., Guzei,, Israel, Fernández, Josephine, Eshon, William T., Raskopf, Steven C., Schmid   +6 more
core   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Substituted Aziridines by Lithiation−Electrophile Trapping of Terminal Aziridines

, 2016
Regio- and stereoselective deprotonation of N-Bus (Bus = tert-butylsulfonyl)-protected terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide generates a nonstabilized (H-substituted) aziridinyl anion that undergoes in situ or external ...
David M. Hodgson (692207), John G. Ward (2462323), Philip G. Humphreys (1357530)   +2 more
core   +1 more source

Synthesis and Evaluation of Biological Activities of Aziridine Derivatives of Urea and Thiourea

Molecules, 2017
In the present paper, we report the synthesis and evaluation of in vitro antimicrobial activities of aziridine-thiourea derivatives. A series of aziridines in reaction with isocyanates and isothiocyanates to obtain urea and thiourea derivatives were used.
Aleksandra Kowalczyk, Adam M. Pieczonka, Michał Rachwalski, Stanisław Leśniak, Paweł Stączek   +4 more
doaj   +1 more source

Formation of Scalemic Aziridines via the Nucleophilic Opening of Aziridines

, 2016
Formation of Scalemic Aziridines via the Nucleophilic Opening of ...
Punit P. Seth (628027), Stephen C. Bergmeier (2042587)   +1 more
core   +1 more source