Results 101 to 110 of about 28,303 (242)

Multi-responsive “turn-on” nanocarriers for efficient site-specific gene delivery in vitro and in vivo [PDF]

, 2016
This is an accepted manuscript of an article published by Wiley in Advanced Healthcare Materials on 25/09/2016, available online: https://doi.org/10.1002/adhm.201600710 The accepted version of the publication may differ from the final published version ...
Bang, Blanco, Brunner, Cai, Chen, Cheng, Choi, Choi, Chuang, Cully, Eliaz, Evans, Fang, Fleige, Franzmann, Grosse, Han, Hatakeyama, He, He, Huth, Jiang, Jiang, Kircheis, Kong, Kurosaki, Lee, Li, Liu, Maeda, Moghimi, Münch, Nomoto, Pack, Panagiotis, Park, Pearson, Peng, Platt, Rajan, Riddles, Saito, Shaheen, Stern, Suk, Tseng, Uthaman, Wagner, Wang, Wang, Wang, Xu, Yamada, Yang, Yao, Yu, Yue, Zhou   +57 more
core   +1 more source

Cathepsin L increases invasion and migration of B16 melanoma [PDF]

, 2007
Background Most cancers express elevated protease levels which contribute to certain aspects of tumor behavior such as growth, metastatic spread, and angiogenesis.
Zhen Yang, James L Cox
core   +2 more sources

Improvement of protocol for detachment assays in B16F10 cells

GSC Biological and Pharmaceutical Sciences
B16F10 (B16) murine melanoma cells have the characteristic of strong adhesion to culture surfaces. The use of trypsin solutions in high doses to release this type of cell is not suitable. When B16F10 cells are released with high concentrations of trypsin they do not form a precipitate after centrifugation and consequently the cells will be lost when ...
Eric Almeida Xavier, Isabela Canavezzi Matias, Anelise Freitas Sandei   +2 more
openaire   +2 more sources

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

Animal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren, Xinpei Wang, Wen Wang, Xingjiu Yang, Mengyuan Li, Jing Du, Ran Gao   +6 more
wiley   +1 more source

Anti-Melanogenesis Activity of 6-O-Isobutyrylbritannilactone from Inula britannica on B16F10 Melanocytes and In Vivo Zebrafish Models

Molecules, 2020
A potential natural melanogenesis inhibitor was discovered in the form of a sesquiterpene isolated from the flowers of Inula britannica, specifically 6-O-isobutyrylbritannilactone (IBL).
Dae Kil Jang, Chau Ha Pham, Ik Soo Lee, Seung-Hyun Jung, Ji Hye Jeong, Han-Seung Shin, Hee Min Yoo   +6 more
doaj   +1 more source

Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution [PDF]

, 2014
Cytokine therapy can activate potent, sustained antitumor responses, but collateral toxicity often limits dosages. Although antibody–cytokine fusions (immunocytokines) have been designed with the intent to localize cytokine activity, systemic dose ...
Kwan, Byron Hua, Navaratna, Tejas, Opel, Cary Francis, Tzeng, Alice, Wittrup, Karl Dane   +4 more
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Tumor-directed evolution of VSVΔ51M produces novel viruses with enhanced antitumor efficacy

Frontiers in Molecular Biosciences
Oncolytic virotherapy has gained enormous attention and is undergoing extensive research, specifically, the Vesicular Stomatitis Virus (VSV). VSV has been shown to provide a potential tool on which many modifications can be introduced to improve its ...
Omar A. Albaradie, Omar A. Albaradie, Abdulaziz Molham Moglan, Abdulaziz Molham Moglan, Yahya Marwan Samman, Yahya Marwan Samman, Fares Fayez Alsayegh, Fares Fayez Alsayegh, Hussam Mohsen Alharbi, Hussam Mohsen Alharbi, Nada Almarghalani, Nada Almarghalani, Khulood Alotaibi, Khulood Alotaibi, Mohammed M. Jalal, Malik A. Altayar, Nizar H. Saeedi, Hanan A. Niaz, Samer Zakri, Samer Zakri, Adnan Almuzaini, Feras Kaboha, Saleh Y. Alabbas, Yasmeen A. Albalawi, Abeer Alsofyani, Abeer Alsofyani, Adrian Pelin, Adrian Pelin, May Abdulaiz Alsayb, May Abdulaiz Alsayb, Shymaa Damfo, Shymaa Damfo, Ahmad Bakur Mahmoud, Ahmad Bakur Mahmoud, Almohanad A. Alkayyal, Almohanad A. Alkayyal   +35 more
doaj   +1 more source

Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]

, 2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V., Lazzara V., Luparello C., Mauro M., Vazzana M.   +4 more
core   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source