Results 111 to 120 of about 16,665 (203)

Hyperdifferentiated murine melanoma cells promote adaptive anti-tumor immunity but activate the immune checkpoint system

OncoImmunology
Accumulating evidence suggests that phenotype switching of cancer cells is essential for therapeutic resistance. However, the immunological characteristics of drug-induced phenotype-switching melanoma cells (PSMCs) are unknown.
Yukie Ando, Yutaka Horiuchi, Sara Hatazawa, Momo Mataki, Akihiro Nakamura, Takashi Murakami   +5 more
doaj   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, Volume 293, Issue 13, Page 4043-4063, July 2026.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Effects of Resveratrol Derivatives on Melanogenesis and Antioxidant Activity in B16F10 Cells

International Journal of Molecular Sciences
Excessive melanogenesis causes abnormal pigmentation and a higher risk of skin disorders (e.g., melanoma). Resveratrol (RSV), a natural polyphenol, exerts antioxidant and anti-aging effects. However, the effects of RSV and its derivatives on melanogenesis remain unclear. This study investigated their effects on melanogenesis and antioxidant activity in
Soyeon Kim, Changho Jhin, Sullim Lee, Ho Sik Rho, Chan Yoon Park   +4 more
openaire   +2 more sources

Action of Carnosic Acid Against Melanoma: A Strategy for Selective Radiosensitization with Protection of Non-Tumoral Cells

Current Issues in Molecular Biology
Carnosic acid (CA) is a phenolic diterpene with high antioxidant activity that supports its radioprotective capacity. This study aims to determine whether the radiosensitizing effect of CA established in B16F10 melanoma cells also occurs in other melanin-
Amparo Olivares, Isabel de la Fuente, Daniel Gyingiri Achel, Ana María Mercado, José Antonio Garcia-Gamuz, María del Rosario Tudela, Miguel Alcaraz   +6 more
doaj   +1 more source

The in vitro and in vivo depigmentation activity of coenzyme Q0, a major quinone derivative from Antrodia camphorata, through autophagy induction in human melanocytes and keratinocytes

Cell Communication and Signaling
Background Coenzyme Q0 (CoQ0), a novel quinone derivative of Antrodia camphorata, has been utilized as a therapeutic agent (including antioxidant, anti-inflammatory, antiangiogenic, antiatherosclerotic, and anticancer agents); however, its depigmenting ...
You-Cheng Hseu, Jou-Tsen Yeh, Chithravel Vadivalagan, Siang-Jyun Chen, Yugandhar Vudhya Gowrisankar, Sudhir Pandey, Yuan-Tai Hsu, Hung-Rong Yen, Hui-Chi Huang, Jhih-Hsuan Hseu, Hsin-Ling Yang   +10 more
doaj   +1 more source

Potential antitumor activity of novel DODAC/PHO-S liposomes

International Journal of Nanomedicine, 2016
Arthur Cássio de Lima Luna,1,2 Greice Kelle Viegas Saraiva,3 Otaviano Mendonça Ribeiro Filho,4 Gilberto Orivaldo Chierice,5 Salvador Claro Neto,5 Iolanda Midea Cuccovia,3 Durvanei Augusto Maria1,2 1Biochemistry and Biophysical Laboratory ...
Luna ACL, Saraiva GKV, Filho OMR, Chierice GO, Neto SC, Cuccovia IM, Maria DA   +6 more
doaj  

Synthesis and Characterization of Sulfonamide-Containing Naphthalimides as Fluorescent Probes

Molecules
A tumor-targeting fluorescent probe has attracted increasing interest in fluorescent imaging for the noninvasive detection of cancers in recent years. Sulfonamide-containing naphthalimide derivatives (SN-2NI, SD-NI) were synthesized by the incorporation ...
Zhi-Wei Liu, Fan Liu, Chun-Tao Shao, Guo-Ping Yan, Jiang-Yu Wu   +4 more
doaj   +1 more source

Melanosomes as Antigen‐Presenting Decoys in Melanoma Immune Evasion

MedComm, Volume 7, Issue 7, July 2026.
Yingqi Kuang, Fangfang Zhou
wiley   +1 more source

Bioactive Lipid Mediator Resolvin D5 Suppresses Melanogenesis in α-MSH-Stimulated B16F10 Cells via ROS-Associated p38/β-Catenin/MITF Regulation. [PDF]

J Microbiol Biotechnol
Choi HJ, Park SJ, Choi JW, Im GE, Lee H, Choi S, Oh DK, Shin KC, Jeong JB.   +8 more
europepmc   +1 more source

A novel prenylflavonoid with efficacy in cancer therapy by targeting ceramide-orchestrated signaling. [PDF]

Front Pharmacol
Du R, Zhang C, Lei H, Gao X, Xiang Q, Zhang Z, Dai Y, Li X, Zhang L, Chen G.   +9 more
europepmc   +1 more source