Results 171 to 180 of about 16,720 (208)

Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells

Nutrition and Cancer, 2017
Cancer cell resistance to chemotherapy is one of the obstacles for better cancer treatment, and inflammatory signaling pathways, such as NF-κB signaling pathway, have been recognized to be involved in such chemoresistance. In this study, we aim to identify a new approach for overcoming cancer chemoresistance by using natural compounds.
Heyao, Ma, Satoru, Yokoyama, Ikuo, Saiki, Yoshihiro, Hayakawa   +3 more
openaire   +2 more sources

Growth of B16F10 cells is enhanced in DJ-1-deficiency pancreas

Biochemical and Biophysical Research Communications, 2023
Association between cancer risk and Parkinson's disease is still debated. DJ-1, a Parkinson's disease (PD)-related gene, is encoded by PARK-7 gene and its deficiency causes early-onset PD. In our last studies, it was found that the immunosuppressive microenvironment established in DJ-1 knockout (KO) mice can enhance metastasis of melanoma cells to ...
Chia-Hung Chien, Ming-Jen Lee, Houng-Chi Liou   +2 more
openaire   +2 more sources

Antiproliferative and proapoptotic actions of okra pectin on B16F10 melanoma cells

Phytotherapy Research, 2010
AbstractThe proliferation and apoptosis of metastatic melanoma cells are often abnormal. We have evaluated the action of a pectic rhamnogalacturonan obtained by hot buffer extraction of okra pods (okra RG‐I) on melanoma cell growth and survival in vitro.
Vayssade, M., Sengkhamparn, N., Verhoef, R.P., Delaigue, C., Goundiam, O., Vigneron, P., Voragen, A.G.J., Schols, H.A., Nagel, M.D.   +8 more
openaire   +2 more sources

Exposure to phenols reduces melanogenesis in B16F10 cells and zebrafish

Aquatic Toxicology
Phenols, ubiquitous environmental contaminants found in water, soil, and air, pose risks to organisms even at minimal concentrations, and many are classified as hazardous pollutants. Skin pigmentation is a natural shield against ultraviolet-induced DNA damage and oxidative stress, pivotal in reducing skin cancer incidences.
Chung-Yu Lin, Chang-Yi Wu, Chia C. Wang, Che-Hsin Lee   +3 more
openaire   +2 more sources

Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent

Cancer Letters, 1996
B16 melanoma has proved to be an ideal model for investigating metastasis. The parental B16F1 line grows as a localized subcutaneous tumor in C57BL/6 or DBA/2 mice. However, by means of successive intravenous transplantation, a subline B16F10 has been established.
R P, Gude, A D, Ingle, S G, Rao
openaire   +2 more sources

Growth and survival signalling in B16F10 melanoma cells in 3D culture

Cell Biology International, 2010
The two‐way communication between the ECM (extracellular matrix) and the cytoplasm via the integrins has many functions in cancer cells, including the suppression of apoptosis. As cells in a 3D (three‐dimensional) architecture resemble the in vivo situation more closely than do cells in more conventional 2D cultures, we have employed a substratum that ...
Oumou, Goundiam, Marie-Danielle, Nagel, Muriel, Vayssade   +2 more
openaire   +2 more sources

Taurine Attenuates Doxorubicin-Induced Toxicity on B16F10 Cells

2017
This study aimed to investigate the effect of doxorubicin co-treatment with taurine on B16F10 melanoma cells. Frequently, Doxorubicin is used in the treatments of many different kinds of cancers, some of which are soft tissue sarcomas, hematological malignancies and carcinomas.
Yon-Suk, Kim, Eun-Kyung, Kim, Jin-Woo, Hwang, Won-Suk, Kim, Woen-Bin, Shin, Sithranga Boopathy, Natarajan, Sang-Ho, Moon, Byong-Tae, Jeon, Pyo-Jam, Park   +8 more
openaire   +2 more sources

Antiproliferative and Antiproteolytic activity of Pentoxifylline in cultures of B16F10 Melanoma cells

Cancer Chemotherapy and Pharmacology, 2005
Pentoxifylline (PTX), a methyl xanthine derivative is widely used as a haemorheological agent in the treatment of peripheral vascular disease. In the present study, we investigated the in vitro effects of PTX on B16F10 melanoma cell proliferation, adhesion and secretion of Matrix metalloproteinases.The toxic range of PTX was evaluated using MTT test ...
Pooja, Dua, Rajiv P, Gude
openaire   +2 more sources

Antineoplastic Effects of Rhodiola crenulata on B16F10 Melanomas

2014
Hypothesis: Rhodiola crenulata extract is derived from Tibetan plant’s roots and has been shown to have anti-cancer properties. Previously, we have shown that Rhodiola extract has toxic effects on B16 F10 mouse melanoma cells in vitro. The purpose of this project was to determine if a daily topical application of Rhodiola extract on melanoma tumors in ...
Dudek, Maxine, Arenas, Richard B., Wong, Kaityln, Mora, Carmen, Bassa, Lotfi M., Schneider, Sallie S.   +5 more
openaire   +1 more source

Treatment of Metastatic Melanoma B16F10 by the Flavonoids Tangeretin, Rutin, and Diosmin

Journal of Agricultural and Food Chemistry, 2005
Melanoma is one of the most frequently metastasizing malignant neoplasias. This study examines an experimental model of pulmonary metastasis and the B16F10 cell subline, highly metastatic in the lung. Antimetastatic effects of the flavonoids tangeretin, rutin, and diosmin were analyzed, and at the same time an analysis of the metastatic activity of ...
Cristina, Martínez Conesa, Vicente, Vicente Ortega, M Josefa, Yáñez Gascón, Miguel, Alcaraz Baños, Manuel, Canteras Jordana, Obdulio, Benavente-García, Julián, Castillo   +6 more
openaire   +2 more sources