Results 211 to 220 of about 28,303 (242)
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Growth and survival signalling in B16F10 melanoma cells in 3D culture
Cell Biology International, 2010The two‐way communication between the ECM (extracellular matrix) and the cytoplasm via the integrins has many functions in cancer cells, including the suppression of apoptosis. As cells in a 3D (three‐dimensional) architecture resemble the in vivo situation more closely than do cells in more conventional 2D cultures, we have employed a substratum that ...
Oumou, Goundiam +2 more
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Taurine Attenuates Doxorubicin-Induced Toxicity on B16F10 Cells
2017This study aimed to investigate the effect of doxorubicin co-treatment with taurine on B16F10 melanoma cells. Frequently, Doxorubicin is used in the treatments of many different kinds of cancers, some of which are soft tissue sarcomas, hematological malignancies and carcinomas.
Yon-Suk, Kim +8 more
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Cancer Chemotherapy and Pharmacology, 2005
Pentoxifylline (PTX), a methyl xanthine derivative is widely used as a haemorheological agent in the treatment of peripheral vascular disease. In the present study, we investigated the in vitro effects of PTX on B16F10 melanoma cell proliferation, adhesion and secretion of Matrix metalloproteinases.The toxic range of PTX was evaluated using MTT test ...
Pooja, Dua, Rajiv P, Gude
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Pentoxifylline (PTX), a methyl xanthine derivative is widely used as a haemorheological agent in the treatment of peripheral vascular disease. In the present study, we investigated the in vitro effects of PTX on B16F10 melanoma cell proliferation, adhesion and secretion of Matrix metalloproteinases.The toxic range of PTX was evaluated using MTT test ...
Pooja, Dua, Rajiv P, Gude
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Treatment of Metastatic Melanoma B16F10 by the Flavonoids Tangeretin, Rutin, and Diosmin
Journal of Agricultural and Food Chemistry, 2005Melanoma is one of the most frequently metastasizing malignant neoplasias. This study examines an experimental model of pulmonary metastasis and the B16F10 cell subline, highly metastatic in the lung. Antimetastatic effects of the flavonoids tangeretin, rutin, and diosmin were analyzed, and at the same time an analysis of the metastatic activity of ...
Cristina, Martínez Conesa +6 more
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Influence of host defenses on the hepatic colonization of B16F10 melanoma cells
Clinical & Experimental Metastasis, 1988To investigate the significance of host immunity in metastasis we have simultaneously evaluated metastatic development and the tumoricidal action of host defenses in an experimental system for liver metastasis which involves the intrasplenic injection of B16F10 melanoma cells in syngeneic mice.
E, Barberá-Guillem +3 more
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Antineoplastic Effects of Rhodiola crenulata on B16F10 Melanomas
2014Hypothesis: Rhodiola crenulata extract is derived from Tibetan plant’s roots and has been shown to have anti-cancer properties. Previously, we have shown that Rhodiola extract has toxic effects on B16 F10 mouse melanoma cells in vitro. The purpose of this project was to determine if a daily topical application of Rhodiola extract on melanoma tumors in ...
Dudek, Maxine +5 more
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Cytotoxic activity of various snake venoms on melanoma, B16F10 and chondrosarcoma
Life Sciences, 1987Elapid, crotalid and viperid venoms were screened in vitro and in vivo for cytotoxicity towards B16F10 melanoma and chondrosarcoma cell lines. The cytotoxic activity of elapid venoms was considerably higher than that of viperid or crotalid venoms. Elapid venoms disrupted the cell membrane within the first hour, leading to cell death.
A, Chaim-Matyas, M, Ovadia
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Transient resistance to B16F10 melanoma growth and metastasis in CD43−/− mice
Melanoma Research, 2002CD43, the major transmembrane sialoglycoprotein of neutrophils, monocytes, T lymphocytes and platelets, is highly glycosylated and its high sialic acid content contributes to the strongly negative charge of cells. In this study the role of CD43 in melanoma development was addressed using CD43 -/- mice (null mutated for the corresponding gene or ...
H T, Fuzii, L R, Travassos
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Substratum acidification and proteinase activation by murine B16F10 melanoma cultures
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1993Murine B16F10 melanoma cells, cultured within 0.7% agarose gels containing the fluorescent proteinase substrate acetamidofluorescein-BSA, catalyze the hydrolysis of the substrate in the region immediately surrounding the cell. Fluorescence ratio measurements on hydrolyzed substrate correlate with an average pH of 5.5 +/- 0.2 in the adjacent substratum ...
P R, Young, S M, Spevacek
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Melanogenesis of Methyl Myristate Loaded Niosomes in B16F10 Melanoma Cells
Journal of Biomedical Nanotechnology, 2013The objective of this study was to compare the charge effect of methyl myristate loaded in neutral (Brij 72/cholesterol at 7:3), cationic (Brij 72/cholesterol/dimethyl dioctadecyl ammonium bromide at 7:3:0.65) and anionic niosomes (Brij 72/cholesterol/dicetyl phosphate at 7:3:0.65) for physicochemical characteristics, cytotoxicity in fibroblasts and ...
Aranya, Manosroi +4 more
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