Results 21 to 30 of about 2,179,011 (259)
Infection and the Perils of B-cell Activation [PDF]
Cancer Discovery, 2015 Abstract Summary: Recent studies have linked aberrant B-cell activation in the context of aberrant immune responses to infectious pathogens to malignant transformation and development of leukemia and lymphoma. A new study in this issue demonstrates that common infections can be drivers of clonal evolution of premalignant B-cell ...
Greaves, Mel, Müschen, Markus
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Multiple regulatory mechanisms control B-1 B cell activation
Frontiers in Immunology, 2012 B-1 cells constitute a unique subset of B cells identified in several species including mice and humans. B-1 cells are further subdivided into B-1a and B-1b subsets as the former but not the later express CD5.
Vishal eSindhava, Subbarao eBondada
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Frontiers in Immunology, 2018 This article describes the work I did in Bill Paul’s lab as a postdoctoral fellow between 1979 and 1983, and to a lesser extent puts that work in the context of other work on B cell activation and antibody responses that was going on in Bill’s lab at ...
Anthony L. DeFranco
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Interleukin-7 and Toll-like receptor 7 induce synergistic B cell and T cell activation. [PDF]
PLoS ONE, 2014 OBJECTIVES: To investigate the potential synergy of IL-7-driven T cell-dependent and TLR7-mediated B cell activation and to assess the additive effects of monocyte/macrophages in this respect.
Angela Bikker +8 more
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生物医学转化B cells play a crucial role in recognizing external antigens through their surface B cell receptor (BCR), essential for generating protective antibodies and immune memory.
Chen Wenjing +4 more
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Dengue Virus Directly Stimulates Polyclonal B Cell Activation.
PLoS ONE, 2015 Dengue infection is associated to vigorous inflammatory response, to a high frequency of activated B cells, and to increased levels of circulating cross-reactive antibodies.
Arturo Ramon Vargas Correa +5 more
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Transgelin-2 in B-Cells Controls T-Cell Activation by Stabilizing T Cell - B Cell Conjugates. [PDF]
PLoS ONE, 2016 The immunological synapse (IS), a dynamic and organized junction between T-cells and antigen presenting cells (APCs), is critical for initiating adaptive immunity.
Bo-Ra Na +6 more
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Frontiers in Immunology, 2018 Immunoproteasome (IP) inhibition holds potential as a novel treatment option for various immune-mediated pathologies. The IP inhibitor ONX 0914 reduced T cell cytokine secretion and Th17 polarization and showed pre-clinical efficacy in a range of ...
Christian Schmidt +8 more
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Frontiers in Immunology, 2019 B-cell activation plays a crucial part in the immune system and is initiated via interaction between the B cell receptor (BCR) and specific antigens.
Jingwen Li +13 more
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Tumor-derived autophagosomes (DRibbles) induce B cell activation in a TLR2-MyD88 dependent manner. [PDF]
PLoS ONE, 2013 Previously, we have documented that isolated autophagosomes from tumor cells could efficiently cross-prime tumor-reactive naïve T cells and mediate tumor regression in preclinical mouse models. However, the effect of tumor-derived autophagosomes, here we
Weixia Li +6 more
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