Results 231 to 240 of about 1,958,602 (263)
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Secretion of soluble pre-B cell receptors by pre-B cells

The Journal of Immunology, 1997
Abstract Pre-B cells can express secretory mu (mu(s))- as well as membrane mu (mu(m))-chains. We evaluated the ability of mu(s)-chains to associate with surrogate light chains and assemble into a pre-B cell receptor (BCR) complex in pre-B cells, and explored whether mu(s)-chains could be exploited to generate a secreted soluble pre ...
K D, Bornemann   +5 more
openaire   +2 more sources

Stereotyped B-Cell Receptor Immunoglobulins in B-Cell Lymphomas

Thorough examination of clonotypic B-cell receptor immunoglobulin (BcR IG) gene rearrangement sequences in patients with mature B-cell malignancies has revealed significant repertoire restrictions, leading to the identification of subsets of patients expressing highly similar, stereotyped BcR IG.
Andreas, Agathangelidis   +4 more
openaire   +2 more sources

The Formation and Selection of Cells Expressing PreB Cell Receptors and B Cell Receptors

1999
The repertoires of B cell receptor (Ig)-expressing B cells are generated during B cell development in a stepwise fashion (Tonegawa 1983). First, DH segments are rearranged to JH segments on the H chain locus at the transition from B220+CD19- proB cells to B220+CD19+ckit+ preB-I cells.
E, ten Boekel   +4 more
openaire   +2 more sources

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen   +2 more
exaly  

Targeting pathological B cell receptor signalling in lymphoid malignancies

Nature Reviews Drug Discovery, 2013
Ryan M Young, Louis M Staudt
exaly  

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