Results 241 to 250 of about 2,912,674 (304)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

bcRflow: a Nextflow pipeline for characterizing B cell receptor repertoires from non-targeted transcriptomic data. [PDF]

NAR Genom Bioinform
Schlegel BT, Morikone M, Mu F, Tang WY, Kohanbash G, Rajasundaram D.   +5 more
europepmc   +1 more source

Prehistory of chronic lymphocytic leukemia: clues from the B-cell receptor. [PDF]

Haematologica
Davi F.
europepmc   +1 more source

Analysis of B-cell receptor repertoire to evaluate immunogenicity of monovalent Omicron XBB.1.5 mRNA vaccines. [PDF]

EJHaem
Funakoshi Y, Yakushijin K, Ohji G, Matsutani T, Doi K, Sakai H, Sasaki T, Kusakabe T, Matsumoto S, Saito Y, Kawamoto S, Yamamoto K, Koyama T, Nagatani Y, Kurata K, Kimbara S, Imamura Y, Kiyota N, Ito M, Minami H.   +19 more
europepmc   +1 more source

B cell adapter for PI 3-kinase (BCAP) coordinates antigen internalization and trafficking through the B cell receptor. [PDF]

Sci Adv
Lagos J, Holder U, Sagadiev S, Montiel-Armendariz A, Li LZ, Pasare C, Hou B, Hamerman JA, Acharya M.   +8 more
europepmc   +1 more source

Inhibition of B cell receptor signaling induced by the human adenovirus species D E3/49K protein. [PDF]

Front Immunol
Hildenbrand A, Cramer P, Bertolotti M, Kaiser NS, Kläsener K, Nickel CM, Reth M, Heim A, Hengel H, Burgert HG, Ruzsics Z.   +10 more
europepmc   +1 more source

T Cells Spatially Regulate B Cell Receptor Signaling in Lymphomas through H3K9me3 Modifications. [PDF]

Adv Healthc Mater
Britto LS, Balasubramani D, Desai S, Phillips P, Trehan N, Cesarman E, Koff JL, Singh A.   +7 more
europepmc   +1 more source

Mutations in the IgG B cell receptor associated with class-switched B cell lymphomas

Wasim L, Chu SWT, Sale B, Pickard L, Léonard S, Zhang L, Tolarová H, Tean ZS, Engels N, Calado DP, Tarte K, Okosun J, Forconi F, Tolar P.   +13 more
europepmc   +1 more source

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B Cell Receptor Signaling

2020
Signaling through the B cell receptor (BCR) plays a critical role at multiple checkpoints of B cell biology. BCR acts as a gatekeeper of the progression of their early development in bone marrow (BM). It is also essential in triggering mechanisms such as clonal deletion and receptor editing to eliminate autoreactive B cells.
Shinya, Tanaka, Yoshihiro, Baba
openaire   +2 more sources