Results 221 to 230 of about 29,942,317 (406)

Mechanisms of central tolerance for B cells

Nature reviews. Immunology, 2017
D. Nemazee
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

IgD in nucleus of pro-B cells promotes pro-B cells proliferation by regulating E2F3 expression. [PDF]

Cell Biosci
Zhang Y, Hou Y, Yu M, Zhang X, Zhang S, Zhu Z, Xu W, Huang J, Qiu X.   +8 more
europepmc   +1 more source

Regulatory B cells: origin, phenotype, and function.

Immunity, 2015
E. Rosser, C. Mauri
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Aging impairs peroxisome biogenesis in human B cells. [PDF]

J Gerontol A Biol Sci Med Sci
Correia J, Roy PS, Holden KG, Kohut ML, Bai H.   +4 more
europepmc   +1 more source

A novel stem cell therapy for hepatitis B virus-related acute-on-chronic liver failure [PDF]

, 2020
Bing Zhu, Shaoli You, Yihui Rong, Qiang Yu, Sa Lv, Fangjiao Song, Hongling Liu, Huaming Wang, Jun Zhao, Dongze Li, Wanshu Liu, Shaojie Xin   +11 more
openalex   +1 more source

Memory B Cells of Mice and Humans.

Annual Review of Immunology, 2017
Florian J. Weisel, M. Shlomchik
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

B-cells and non-B-cells immunoglobulins expression in canine perianal gland tumours: a preliminary study. [PDF]

Front Vet Sci
Rifici C, Lusi EA, Giambrone G, Ieni A, Napoli E, Mannarino C, Zappone V, Mazzullo G.   +7 more
europepmc   +1 more source