Biology of Beige Adipocyte and Possible Therapy for Type 2 Diabetes and Obesity
International Journal of Endocrinology, 2016 All mammals own two main forms of fat. The classical white adipose tissue builds up energy in the form of triglycerides and is useful for preventing fatigue during periods of low caloric intake and the brown adipose tissue instead of inducing fat ...
Fernando Lizcano, Diana Vargas
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EBF2 promotes the recruitment of beige adipocytes in white adipose tissue
Molecular Metabolism, 2016 Objective: The induction of beige/brite adipose cells in white adipose tissue (WAT) is associated with protection against high fat diet-induced obesity and insulin resistance in animals.
Rachel R. Stine +6 more
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Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]
, 2018 Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G. +13 more
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Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. [PDF]
, 2019 Prolonged cold exposure stimulates the recruitment of beige adipocytes within white adipose tissue. Beige adipocytes depend on mitochondrial oxidative phosphorylation to drive thermogenesis.
Lee, Sanghoon +7 more
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Functional Implications of DNA Methylation in Adipose Biology. [PDF]
, 2019 The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
core
State permutations from manipulation of near level-crossings [PDF]
, 2002 We discuss some systematic methods for implementing state manipulations in systems formally similar to chains of a few spins with nearest-neighbor interactions, arranged such that there are strong and weak scales of coupling links. States are permuted by
A. Beige +11 more
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Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis. [PDF]
, 2020 Cold stimuli and the subsequent activation of β-adrenergic receptor (β-AR) potently stimulate adipose tissue thermogenesis and increase whole-body energy expenditure.
Ferro, Marc D +8 more
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Heartbreak hotel: a convergence in cardiac regeneration [PDF]
, 2016 In February 2016, the Company of Biologists hosted an intimate gathering of leading international researchers at the forefront of experimental cardiovascular regeneration, with its emphasis on ‘Transdifferentiation and Tissue Plasticity in Cardiovascular
Schneider, MD
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A Literature Review On Intermittent Fasting [PDF]
, 2020 Intermittent fasting has been instructed in the Bible as an implied part of daily living. This paper has reviewed the physical benefits of intermittent fasting. In healthy test subjects, it has led to higher levels of autophagy, gut health, and lifespan.
Carrero, Kylie
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Coordinate Functional Regulation between Microsomal Prostaglandin E Synthase-1 (mPGES-1) and Peroxisome Proliferator-activated Receptor y (PPARy) in the Conversion of White-to-brown Adipocytes [PDF]
, 2017 Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor and a master regulator of adipogenesis. Microsomal prostaglandin E (PGE) synthase-1 (mPGES-1) is an inducible enzyme that couples with cyclooxygenase-2 for the ...
Arroyo, Vicente +9 more
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