Results 31 to 40 of about 38,179 (226)

Inducible UCP1 silencing: A lentiviral RNA-interference approach to quantify the contribution of beige fat to energy homeostasis. [PDF]

PLoS ONE, 2019
Energy consuming, heat-producing beige adipocytes, located in classic white adipose tissue (WAT), hold promise for the treatment of obesity. Few reports have quantitatively assessed the contribution of browned 'WAT' to energy expenditure. There is a need
Nicole Wen Mun Khor, Michael M Swarbrick, Jenny E Gunton   +2 more
doaj   +2 more sources

Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes

Frontiers in Endocrinology, 2020
Brown adipose tissue (BAT) and beige adipose tissue dissipate metabolic energy and mediate nonshivering thermogenesis, thereby boosting energy expenditure. Increasing the browning of BAT and beige adipose tissue is expected to be a promising strategy for
Ya-Nan Duan, Ya-Nan Duan, Xiang Ge, Hao-Wen Jiang, Hong-Jie Zhang, Yu Zhao, Jin-Long Li, Jin-Long Li, Wei Zhang, Jing-Ya Li   +9 more
doaj   +2 more sources

Protective role for beige fat [PDF]

Nature Genetics, 2014
Kyle Vogan
openalex   +2 more sources

Brown and Beige Fat: Therapeutic Potential in Obesity

Indonesian Biomedical Journal, 2014
BACKGROUND: The epidemic of obesity and type 2 diabetes presents a serious challenge to scientific and biomedical communities worldwide. There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the ...
Anna Meiliana, Andi Wijaya
doaj   +3 more sources

The miR-182-5p/FGF21/acetylcholine axis mediates the crosstalk between adipocytes and macrophages to promote beige fat thermogenesis. [PDF]

JCI Insight, 2021
Meng W, Xiao T, Liang X, Wen J, Peng X, Wang J, Zou Y, Liu J, Bialowas C, Luo H, Zhang Y, Liu B, Zhang J, Hu F, Liu M, Dong LQ, Zhou Z, Liu F, Bai J.   +18 more
europepmc   +3 more sources

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis [PDF]

Cell, 2014
Jonathan Z Long, James P White, Katrin J Svensson   +2 more
exaly   +2 more sources

LIGHT/TNFSF14 signaling attenuates beige fat biogenesis [PDF]

The FASEB Journal, 2018
ABSTRACT The physiologic signals that regulate beige adipogenesis remain incompletely understood, especially those that limit browning and prevent overexpenditure of energy. In this study, the TNF family member cytokine lymphotoxin‐like inducible protein that competes with glycoprotein D for herpesvirus entry on T
Yanbo Kou, Qingya Liu, Wenli Liu, Hongxiang Sun, Ming Liang, Fanyun Kong, Bo Zhang, Yanxia Wei, Zhuanzhuan Liu, Yugang Wang   +9 more
openalex   +3 more sources

Identification of specific microbiota members that induce beige fat biogenesis in response to dietary cues [PDF]

Honda K, Tanoue T, Nagayama M, Roochana A, Zimmerman S, Ashenberg O, Jain T, Sasajima S, Takeshita K, Hetherington N, Okahashi N, Ueda M, Konishi M, Nakayama Y, Minoda A, Skelly A, Minokoshi Y, Pucci N, Mende D, Arita M, Yamamoto H, Watanabe S, Miura K, Suda W, Atarashi K, Matsushita M, Kajimura S, Plichta D, Saito M, Xavier R.   +29 more
europepmc   +2 more sources

Going immune on beige fat [PDF]

Science-Business eXchange, 2014
Two independent teams at UCSF and Harvard have found an immune-regulated pathway for beige fat formation and a hormone, METRNL, that activates it. Ember Therapeutics has an option to license the molecule, which could represent a new way to treat obesity.
Kai-Jye Lou
openalex   +3 more sources

Noncanonical beige fat thermogenesis [PDF]

Nature Reviews Endocrinology, 2017
Conor A. Bradley
openalex   +2 more sources