Results 21 to 30 of about 25,772 (306)

Kinetics and Mechanism of Hydrolysis of Benzimidazolylcarbamates [PDF]

, 2007
Synthesis of new 2-aminobenzimidazole-1-carbamates was accomplished by carbamoylation of 2-aminobenzimidazole using different substituted phenyl chloroformates. The aqueous hydrolysis of the new compounds was examined in the pH range 1-13 at 25 oC.
Corte Real, M., Iley, J., Norberto, F.P., Santos, S.P., Silva, D.B.   +4 more
core   +2 more sources

Modeling solid state stability for speciation: a ten-year long study [PDF]

, 2019
Speciation studies are based on fundamental models that relate the properties of biomimetic coordination compounds to the stability of the complexes. In addition to the classic approach based on solution studies, solid state properties have been recently
Buiarelli, Francesca, Carcassi, Elena, Gullifa, Giuseppina, Materazzi, Stefano, Risoluti, Roberta, Wo, Li W.   +5 more
core   +1 more source

The Benzimidazole Derivatives, B1 (N-[(1H-Benzimidazol-2-yl)Methyl]-4-Methoxyaniline) and B8 (N-{4-[(1H-Benzimidazol-2-yl)Methoxy]Phenyl}Acetamide) Attenuate Morphine-Induced Paradoxical Pain in Mice

Frontiers in Neuroscience, 2019
Despite being routinely used for pain management, opioid use is limited due to adverse effects such as development of tolerance and paradoxical pain, including thermal hyperalgesia and mechanical allodynia.
Zahida Idris, Muzaffar Abbas, Humaira Nadeem, Arif-ullah Khan   +3 more
doaj   +1 more source

Structure-based design of functionalized 2-substituted and 1,2-disubstituted benzimidazole derivatives and their in vitro antibacterial efficacy

Journal of Advanced Research, 2017
The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives to investigate their antibacterial diversity for possible future drug design.
Olayinka O. Ajani, Olayinka O. Tolu-Bolaji, Shade J. Olorunshola, Yuxia Zhao, Damilola V. Aderohunmu   +4 more
doaj   +1 more source

STK295900, a Dual Inhibitor of Topoisomerase 1 and 2, Induces G2 Arrest in the Absence of DNA Damage [PDF]

, 2013
STK295900, a small synthetic molecule belonging to a class of symmetric bibenzimidazoles, exhibits antiproliferative activity against various human cancer cell lines from different origins.
A Balmain, A Satyanarayana, AK Larsen, AW Murray, AY Chen, B Clifford, B Narasimhan, Bo Yeon Kim, BY Kim, CC Chiu, CS Downes, DR Kellogg, DV Bulavin, EA Nigg, EP Rogakou, F Foijer, F Hans, H van Attikum, J Bartek, J Bonnet, J Mann, J Pines, J Rudolph, Jae-Hyuk Jang, JH Trembley, Jian-Ting Zhang, JJ Bower, JJ Champoux, JL Nitiss, Jong Seog Ahn, K Kristjansdottir, K Uto, Krisada Sakchaisri, Kyung Sang Lee, L Antoni, L He, MA Jordan, Nak Kyun Soung, PA Futreal, Raymond Leo Erikson, RT Abraham, S Jin, S Patel, SM Vos, Sun-Ok Kim, Thimmegowda N. R., VA Smits, WM Bonner, WR Taylor, X Cai, Y Pommier, Y Shiloh, Y Wei, YH Hsiang, Yong Tae Kwon, Young Sang Kim, YP Tsao, Yukihiro Asami   +57 more
core   +2 more sources

Antimicrobial potential of 1H-benzo[d]imidazole scaffold: a review

BMC Chemistry, 2019
Background Benzimidazole is a heterocyclic moiety whose derivatives are present in many of the bioactive compounds and posses diverse biological and clinical applications.
Sumit Tahlan, Sanjiv Kumar, Balasubramanian Narasimhan   +2 more
doaj   +1 more source

Sensitivity of Haemonchus contortus to anthelmintics using different in vitro screening assays: a comparative study

Parasites & Vectors, 2022
Background Helminthiasis and resistance to commercial anthelmintic compounds are major causes of economic losses for livestock producers, resulting in an urgent need for new drugs and reliable in vitro screening tests capable of detecting potentially ...
Beatriz Munguía, Jenny Saldaña, Magdalena Nieves, María Elisa Melian, Manuela Ferrer, Ramiro Teixeira, Williams Porcal, Eduardo Manta, Laura Domínguez   +8 more
doaj   +1 more source

Spinal cystic echinococcosis - a systematic analysis and review of the literature : part 2. treatment, follow-up and outcome [PDF]

, 2013
Bone involvement in human cystic echinococcosis (CE) is rare, but affects the spine in approximately 50% of cases. Despite significant advances in diagnostic imaging techniques, surgical treatment and introduction of pharmacological therapy, spinal ...
Blum, Johannes, Brunetti, Enrico, Goblirsch, Sam, Neumayr, Andreas, Tamarozzi, Francesca   +4 more
core   +3 more sources

Synthesis and second-order nonlinear optical properties of new chromophores containing benzimidazole, thiophene and pyrrole heterocycles [PDF]

, 2007
A new series of thermally stable benzimidazole-based nonlinear optical (NLO) chromophores 4-5 has been developed. These chromophores possess a thienylpyrrolyl pi-conjugated system attached to functionalized benzimidazole heterocycles.
Batista, Rosa Maria Ferreira, Belsley, M., Costa, Susana P. G., Raposo, M. Manuela M.   +3 more
core   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source