Results 21 to 30 of about 27,476 (269)

Physico-chemical characterization and anti- microbial activity of copper(II) complexes with 2-amino and 2-methylbenzimidazole derivatives [PDF]

, 2004
Copper(II) chloride, in warm ethanolic solution, reacted with 2-amino and 2-methylbenzimidazole derivatives to give complexes of the formula CuL2Cl2·nH2O, where L=1-benzyl-2-aminobenzimidazole 1-(4-methylbenzyl)-2-aminobenzimidazole, 1-benzyl-2 ...
Markov Siniša L., Podunavac-Kuzmanović Sanja O., Vojinović Ljiljana S.   +2 more
core   +1 more source

Spinal cystic echinococcosis - a systematic analysis and review of the literature : part 2. treatment, follow-up and outcome [PDF]

, 2013
Bone involvement in human cystic echinococcosis (CE) is rare, but affects the spine in approximately 50% of cases. Despite significant advances in diagnostic imaging techniques, surgical treatment and introduction of pharmacological therapy, spinal ...
Blum, Johannes, Brunetti, Enrico, Goblirsch, Sam, Neumayr, Andreas, Tamarozzi, Francesca   +4 more
core   +3 more sources

The Benzimidazole Derivatives, B1 (N-[(1H-Benzimidazol-2-yl)Methyl]-4-Methoxyaniline) and B8 (N-{4-[(1H-Benzimidazol-2-yl)Methoxy]Phenyl}Acetamide) Attenuate Morphine-Induced Paradoxical Pain in Mice

Frontiers in Neuroscience, 2019
Despite being routinely used for pain management, opioid use is limited due to adverse effects such as development of tolerance and paradoxical pain, including thermal hyperalgesia and mechanical allodynia.
Zahida Idris, Muzaffar Abbas, Humaira Nadeem, Arif-ullah Khan   +3 more
doaj   +1 more source

Quantitative structure-activity relationship of some 1-benzylbenzimidazole derivatives as antifungal agents [PDF]

, 2007
In the present study, the antifungal activity of some 1-benzylbenzimidazole derivatives against yeast Saccharomyces cerevisiae was investigated. The tested benzimidazoles displayed in vitro antifungal activity and minimum inhibitory concentration (MIC ...
Barna Dijana J., Cvetković Dragoljub D., Podunavac-Kuzmanović Sanja O.   +2 more
core   +1 more source

Structure-based design of functionalized 2-substituted and 1,2-disubstituted benzimidazole derivatives and their in vitro antibacterial efficacy

Journal of Advanced Research, 2017
The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives to investigate their antibacterial diversity for possible future drug design.
Olayinka O. Ajani, Olayinka O. Tolu-Bolaji, Shade J. Olorunshola, Yuxia Zhao, Damilola V. Aderohunmu   +4 more
doaj   +1 more source

One-pot Synthesis of Substituted Benzimidazole Derivatives under Ultrasonic Irradiation Using ZnFe2O4 Reusable Catalyst

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2022
Herein, an efficient one-pot synthesis is described, of substituted benzimidazole derivatives (3a-j) from a condensation of various o-phenylenediamine (1a-j) aromatic aldehyde (2a-j) using ZnFe2O4 as a nano-catalyst under ultrasonic irradiation ...
Dhanraj Kamble, Anil Shankarwar, Yuvraj Sarnikar, Radhakrushna Tigote, Mubarak Shaikh, Pravin Chavan   +5 more
doaj   +1 more source

Benzimidazole and its derivatives: Recent Advances (2020–2022)

Results in Chemistry, 2023
Benzimidazoles are fused heterocyclic ring systems containing two nitrogen atoms. They have vital therapeutic significance in drug discovery. Many clinically approved drugs have been developed from benzimidazole, and these include liarozole and ...
Oluwakemi Ebenezer, Funsho Oyetunde-Joshua, Oluwadamilare D. Omotoso, Micheal Shapi   +3 more
doaj   +1 more source

Relationship between intraocular pressure lowering effect and chemical structure of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole derivatives

Data in Brief, 2018
This article contains data that relate to the study carried out in the work of Marcus et al. (2018) [1]. Data represent an information about pharmacophore analysis of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole derivatives and results of
Pavel Vassiliev, Igor Iezhitsa, Renu Agarwal, Adrian Julian Marcus, Alexander Spasov, Olga Zhukovskaya, Vera Anisimova   +6 more
doaj   +1 more source

Antimicrobial potential of 1H-benzo[d]imidazole scaffold: a review

BMC Chemistry, 2019
Background Benzimidazole is a heterocyclic moiety whose derivatives are present in many of the bioactive compounds and posses diverse biological and clinical applications.
Sumit Tahlan, Sanjiv Kumar, Balasubramanian Narasimhan   +2 more
doaj   +1 more source

Chiral benzimidazoles as hydrogen bonding organocatalysts [PDF]

, 2015
Several bifunctional organocatalysts bearing the benzimidazole unit have been designed in order to act as bifunctional systems by hydrogen bonding. Chiral 2-aminobenzimidazoles are conformational rigid guanidines able to catalyze enantioselectively ...
Nájera, Carmen, Yus, Miguel
core   +2 more sources